Scleral window surgery and topical mitomycin C for nanophthalmic uveal effusion complicated by renal failure: case report

Abstract

Topical MMC might relieve the blocked transscleral outflow of intraocular fluid in the small area of a sclerostomy in young patients with nanophthalmos or in patients with renal failure in whom uveal effusion occurs repeatedly.

Scleral punch method with topical mitomycin c for safe revision of failed deep sclerectomy in nanophthalmic uveal effusion syndrome

“…Full-thickness cuts may be safer with the scleral punch because a rounded instrument rather than a sharp edge is presented against the choroid. We also applied MMC to inhibit further scarring, and we propose that this might be used more widely in UES, as has been recommended by others [8]. Re-exploration in this case confirmed that the previous full-thickness scleral windows had become occluded by fibrosis and scarring.…”

Scleral resection in chronic central serous chorioretinopathy complicated by exudative retinal detachment

“…MMC has been used successfully for its modulatory effects on wound healing in multiple ocular surgeries including trabeculectomy, pterygium excision, kerato-refractive surgeries, and sclerectomy for retinal detachment in nanophthalmos [11–13]. In scleral resection, MMC is thought to reduce scarring of the sclerectomy bed and prevent recurrence of the exudative retinal detachment due to the regeneration of thick sclera with abnormally arranged collagen fibers [13].…”

“…In scleral resection, MMC is thought to reduce scarring of the sclerectomy bed and prevent recurrence of the exudative retinal detachment due to the regeneration of thick sclera with abnormally arranged collagen fibers [13]. Reported complications of MMC include hypotony secondary to thin cystic bleb following trabeculectomy, endophthalmitis, and corneal or scleral melting [12].…”

Bilateral Nanophthalmic Uveal Effusion Syndrome

“…[18][19][20] Uveal effusion syndrome has been described in association with renal failure, and the underlying mechanism may be similar to that of our hypothesis. 21 However, our subject had normal plasma albumin levels and no signs of nephropathy.…”