Treatment of Furcation Involvement Using Autogenous Tooth Graft With 1‐Year Follow‐Up: A Case Series

Abstract

Introduction The objective of this study was to clinically evaluate an autogenous tooth graft (ATG) as a novel bone graft material in the treatment of Class II furcation defects. ATG is prepared at chairside from a freshly extracted tooth to be used immediately for bone regeneration. It has an advantage over the autogenous and other bone graft materials as it is non‐immunogenic, inexpensive, easily available, and lacks donor‐site morbidity. Case Presentation This study was conducted on three middle‐aged (35 to 55 years) male patients, who had at least one mandibular molar with Class II furcation involvement (a total of 5 sites) and one tooth that required extraction because of poor prognosis and was not endodontically treated. At 9 and 12 months, the mean reductions in horizontal probing depth were (1.40 ± 0.57 mm) and (1.52 ± 0.59 mm), respectively, and the mean gains in linear bone‐fill were (3.90 ± 0.15 mm) and (5.33 ± 0.10 mm), respectively. Conclusions Within the limitation of this study, ATG exhibited ideal properties for alveolar bone regeneration. In addition, this study outlines the chairside method to prepare a graft and highlights the improvement in clinical and radiographic parameters at 9 and 12 months.

Autologous Deciduous Tooth-Derived Material for Alveolar Ridge Preservation: A Clinical and Histological Case Report

“…The outcomes they obtained were promising, since bone volume changes were significantly lower in the test group than in sites left to heal spontaneously [18]. Similar results were found also in more demanding bone regeneration procedures, such as the treatment of furcation defects [19].…”

Physicochemical and osteogenic properties of chairside processed tooth derived bone substitute and bone graft materials

“…The release of BMP2 protein was related to human primary osteoblasts migration in a dose-dependent manner, suggesting it might be involved in the chemotactic recruitment of osteoblasts during bone formation in addition to its function as a differentiation enhancer 51) . The BMP2 also was found preserved in mammal teeth, which can be gradually released even long after extraction or post-chemical processing 55,[57][58][59] making a successful clinical outcome for DDM or TDBS as a grafting material 24,33,[60][61][62] . In the present study, BMP2 protein was found in supernatant containing TDBS prepared chairside after decontaminating steps, ensuring that this novel technique of preparing TDBS can preserve substantial proteins in dentin matrix i.e., BMP2, and this protein could also be able released from the matrix without the demineralizing process.…”

Otojen Di̇ş Kemi̇k Grefti̇ni̇n Bi̇yoloji̇k Özelli̇kleri̇ Ve Kli̇ni̇k Kullanimi

“…52,62 Otojen Diş Kemik Grefti Eldesi 1993 yılında, insan dişlerinin kemik grefti olarak kullanıldığı deneysel çalışmalara başlanmıştır. [64][65][66][67][68][69] 2008 yılında, ODKG geliştirilmiştir. İlk klinik çalışma olarak, Kim ve arkadaşları 9 diş çekimi sonrası implant cerrahisi planlanan hastalarda, kemik ogmentasyonunda ODKG kullanmışlardır.…”

“…Bu işlemin ardından, diş yüzeyinden mine ve sement dokusu uzaklaştırılarak dentin dokusu korunur. 64,66,69 Dentin dokusu, blok şeklinde kullanılabildiği gibi otomatik programlı ve farklı boyutlarda greft eldesine izin veren cihazlar veya manuel olarak el aletleri ile toz haline getirilebilir. [64][65][66][67][68][69] Ike ve Urist 33 tüm bu liyofilizasyon ve sterilizasyon işlemlerinden geçirilmesine rağmen dentin dokusunun organik yapısının korunduğunu ve elde edilen dentin dokusunun, ODKG'nin temel içeriğini oluşturduğunu belirtmişlerdir.…”