Autologous Deciduous Tooth-Derived Material for Alveolar Ridge Preservation: A Clinical and Histological Case Report

Abstract

The management of the alveolar socket is fundamental to create conditions that would allow the positioning of dental implants in the same site, when required. A number of biomaterials were described in scientific literature to be used for alveolar socket preservation immediately after tooth extraction: autogenous grafts, allograft (of various origin), and synthetic products. Among the autogenous biomaterials, some authors proposed the use of autogenous dentin and/or enamel, retrieved from teeth, adequately managed, and purified. The present case report with two-year follow-up shows one case of alveolar socket preservation by using tooth graft material that was subsequently treated with one implant-supported rehabilitation in the same site. The paper presents clinical and histological outcomes and confirms the feasibility of adopting such autogenous biomaterial in standard procedures.

Autologous Tooth Graft: Innovative Biomaterial for Bone Regeneration. Tooth Transformer® and the Role of Microbiota in Regenerative Dentistry. A Systematic Review

“…A case report, with two-year follow-up, exposed that socket preservation was possible using dental grafting material, and the same site was subsequently treated with implant-supported rehabilitation [ 72 ].…”

“…Bone remodeling is a constant and complex process for bone tissues in the body and could cause resorption of alveolar bone when a tooth is no longer in place. To compensate for insufficient available bone volume, a number of surgical procedures designed to augment bone volume are described and validated in the scientific literature [ 72 ]. As we know from the literature, after tooth extraction, healing of the socket happens through the sequence of many steps, beginning with the stabilization of the clot, the formation of fibrin, and, finally, the recruitment of osteoblasts that will be in charge of the formation of new bone.…”

“…As we know from the literature, after tooth extraction, healing of the socket happens through the sequence of many steps, beginning with the stabilization of the clot, the formation of fibrin, and, finally, the recruitment of osteoblasts that will be in charge of the formation of new bone. Several biomaterials and techniques for alveolar volume preservation have been reported, with many functionalities (osteoconduction, osteoinduction, or even stimulation) according to the features of each material [ 72 ].…”

“…Human dentin and bone exhibit many similarities in regard to mineralization. In fact, after demineralization, both DDM and DBM are made up predominantly of type I collagen (90%) and NCP and, among them, growth factors; therefore, human DDM is a bio-collagen scaffold containing osteoinductive growth factors that supply an appropriate setting to promote new bone formation [ 72 ].…”

Immediate implant positioning using tooth‐derived bone substitute material for alveolar ridge preservation: Preliminary results at 6 months

“…This material could be derived directly from processing the extracted tooth and can be reinserted into the patient in the form of microgranules, after a specific procedure that involves the utilization of one device. The literature presents different studies indicating its positive regenerative potential and guaranteeing its safety from the microbiological point of view (Minetti, Giacometti, et al, 2020 ; Minetti, Taschieri, et al, 2020 ). Osteoinductive properties and the presence of bone morphogenetic proteins (BMPs) were demonstrated for demineralized dentin by studies published in the last decades (Bang, 1967 ; Bessho et al, 1991 ).…”