Treatment of Early Hepatic Artery Thrombosis After Liver Transplantation

Grodzicki, Mariusz; Anysz-Grodzicka, Agnieszka; Remiszewski, Piotr; Cieślak, Bartosz; Kotulski, Marcin; Kalinowski, Piotr; Paluszkiewicz, Rafał; Rowiński, Olgierd; Krawczyk, Marek

doi:10.1016/j.transproceed.2011.08.028

Cited by 24 publications

(14 citation statements)

References 9 publications

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“…(1, 6, 7, 10, 14, 15, 18, 19, 24, 27-34) Hepatic artery thrombosis was reported by 13 studies, with a pooled incidence of 0.045 (95% CI=0.031 to 0.062). Rates of hepatic artery stenosis were reported by 5 studies with a combined incidence of 0.045 (95% CI = 0.015 to 0.089).…”

Section: Resultsmentioning

confidence: 99%

A meta-analysis of complications following deceased donor liver transplant

McElroy¹,

Daud²,

Davis³

et al. 2014

The American Journal of Surgery

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Background Liver transplantation is a complex surgery associated with high rates of postoperative complications. While national outcomes data are available, national rates of most complications are unknown. Data Sources A systematic review of the literature reporting rates of postoperative complications between 2002 and 2012 was performed. A cohort of 29,227 deceased donor liver transplant recipients from 74 studies was used to calculate pooled incidences were for 17 major postoperative complications. Conclusions This is the first comprehensive review of postoperative complications after liver transplantation and can serve as a guide for transplant and non-transplant clinicians. Efforts to collect national data on complications, such as through the National Surgical Quality Improvement Program, would improve the ability to provide patients with informed consent, serve as a tool for individual center performance monitoring, and provide a central source against which to measure interventions aimed at improving patient care.

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Section: Resultsmentioning

confidence: 99%

A meta-analysis of complications following deceased donor liver transplant

McElroy¹,

Daud²,

Davis³

et al. 2014

The American Journal of Surgery

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“…Roux-en-Y biliary reconstruction, graft revision, and reoperation are also identified risk factors (28). Graft ischemia in liver transplant recipients caused by HAS and/or HAT contributes significantly to mortality and graft loss after liver transplantation (18,27,30,31).…”

Section: Hepatic Artery Thrombosismentioning

confidence: 99%

“…There are currently two major therapeutic options for the treatment of these arterial complications: endovascular interventions and surgery (11,31,32). The former includes intra-arterial thrombolysis, embolization, percutaneous transluminal angioplasty (PTA), and stent placement.…”

Section: Treatment Approachesmentioning

confidence: 99%

“…Therefore, early identification and treatment is critical to recover blood flow to rescue the graft. Doppler ultrasonography examination performed at 24 and 48 hr after transplantation can be used as a screening protocol for the early diagnosis of HAT (31). Magnetic resonance angiography (MRA) complements Doppler ultrasound to exclude significant hepatic artery stenosis (44).…”

Section: Hepatic Arterial Thrombosismentioning

confidence: 99%

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Surgical and endovascular treatment of hepatic arterial complications following liver transplant

Chen

Weinstein

Black

et al. 2014

Clinical Transplantation

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Vascular complications after liver transplantation increase post-operative morbidity and contribute to the incidence of retransplantation. Vascular complications comprise arterial, caval, and portal venous pathology, with the majority of complications being arterial in etiology, including anastomotic stricture, pseudoaneurysm, and thrombosis. There are two major therapeutic options for the treatment of these arterial complications: endovascular intervention and surgery. The former includes intra-arterial thrombolysis, embolization, percutaneous transluminal angioplasty, and stent placement. The latter includes thrombectomy, reanastomosis, and retransplantation. Although surgical treatment has been considered the first choice for management in the past, advances in endovascular intervention have increased and make it a viable therapeutic option following orthotopic liver transplantation. This review focuses on the role of surgical and endovascular therapy in the management of hepatic arterial complications after liver transplantation.

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“…After diagnosis of HAT is established, interventional radiologic approaches using thrombolytic agents such as percutaneous transluminal angioplasty or urokinase, balloon dilation, and intraluminal stent placement should be the first therapeutic steps 54. With revascularization and conservative treatment, 67% to 100% of patients were treated successfully without need for retransplantation 55–57…”

Section: Transplantation and Surgical Techniquesmentioning

confidence: 99%

Current Concepts in Pediatric Liver Transplantation

Emre

Umman

Çimşit

et al. 2012

Mount Sinai J Medicine

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Liver transplantation is the definitive treatment for end-stage liver disease in both children and adults. Advances over the last 2 decades have resulted in excellent patient and graft survival rates in what were previously cases of fatal disorders. These developments have been due to innovations in surgical technique, increased surgical experience, refinements in immunosuppressive regimens, quality improvements in intraoperative anesthetic management, better understanding of the pathophysiology of the liver diseases, and better preoperative and postoperative care. Remarkably, the use of split-liver and living-related liver transplantation surgical techniques has helped mitigate the well-recognized national organ shortage. This review will discuss the major aspects of pediatric liver transplantation as it pertains to indication for transplantation, recipient selection and listing for orthotopic liver transplantation, pre-orthotopic liver transplantation care of children, optimal timing of orthotopic liver transplantation, surgical technical considerations, postoperative care and complications, and patient and graft survival outcomes.

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Treatment of Early Hepatic Artery Thrombosis After Liver Transplantation

Cited by 24 publications

References 9 publications

A meta-analysis of complications following deceased donor liver transplant

A meta-analysis of complications following deceased donor liver transplant

Surgical and endovascular treatment of hepatic arterial complications following liver transplant

Current Concepts in Pediatric Liver Transplantation

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