Treatment of digit ulcers in a patient with Buerger's disease by using cervical spinal cord stimulation -a case report-

Ryu, Sang Wook; Jeon, Hee Jung; Cho, Sam Soon; Choi, Rak Min; Yoon, Jin Sun; Ko, Hong Seok; Lee, Jae Do

doi:10.4097/kjae.2013.65.2.167

Cited by 8 publications

(12 citation statements)

References 13 publications

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“…[34] There are also case reports of successful treatment of SCS in Burger's disease and Raynaud's disease. [35][36][37][38] In the follow-up of treatment in critical ischemic disease, many examinations showing perfusion have been identified. In addition to ankle brachial index (ABI) and transcutaneous oxygen tension (TcPO2), at previous studies MR angiography perfusion (MRAP), technetium-99m-labeled Methoxyisobutyl isonitrile (99mTc-MIBI) -single-photon emission computed tomography (SPECT), and Thallium-201 (201T1) -SPECT were used to show microvasculer perfusion insufficiency in critical ischemic disease.…”

Section: Discussionmentioning

confidence: 99%

Spinal cord stimulator for the treatment of ischemic pain-Burger’s Disease and Raynaud’s Disease: A report of 2 cases and literature review

Ertilav¹

2020

Agri

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İskemik ağrı, ekstremitelere yetersiz kan akımıyla sonuçlanan bir grup hastalığın ana semptomudur. Bu semptomatolojide iki ana hastalık ayırt edilir: kritik vasküler hastalık ve Raynaud fenomeni. Kritik vasküler hastalık diabetes mellitus veya hipertansiyonun neden olduğu aterosklerozun zemininde gelişmektedir. Raynaud fenomeni primer ve sekonder forma ayrılır. Primer form vazospazmdan nedenlidir ve altta yatan bir neden yoktur. İkincil form, altta yatan bağ dokusu veya romatizmal hastalıklar, tromboangit obliterans (Burger hastalığı) gibi periferal vasküler hastalıklar ile ilişkilidir. Raynaud hastalığında klinik bulgular, soğuğa maruz kalma ile morarma, soğukluk, ağrılı parestezi gibi vasomotor değişiklikler ve kronik iskemiden kaynaklanan ülserlerdir. Kritik iskemik hastalıkta klinik prezentasyon, erken evre için intermitten kladikasyo ve ileri evrelerde istirahat ağrısı, kangren, nekroz ve trofik değişiklikler de eklenir. Raynaud hastalığının erken evrede tedavisi medikal ve konservatiftir. İleri evre iskemik vasküler hastalık, tıbbi tedaviye dirençli ağrı, endovasküler tedaviye yetersiz yanıt, inoperabl vakalar gibi durumlarda sempatektomi ve spinal cord stimülasyonu (SKS) gibi girişimler uygulanabilir. SKS vazodilatör mediatörler ile vasküler rezistansı azaltır ve kan akımınıı arttırır. SKS ayrıca sempatik vazokonstriksiyonu baskılar, doku kanlanmasını arttırır, doku hasarını azaltır, ülser iyileşmesini sağlar ve ağrıyı azaltır. Bu olgu bildirimlerinde dirençli Raynaud hastalığının ve ileri evre Burger hastalığının SKS ile başarılı bir şekilde tedavi edildiğini gösterdik.

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Section: Discussionmentioning

confidence: 99%

Spinal cord stimulator for the treatment of ischemic pain-Burger’s Disease and Raynaud’s Disease: A report of 2 cases and literature review

Ertilav¹

2020

Agri

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“…The absence of distal vascular targets makes surgical revascularization challenging. Endovascular treatment modalities have demonstrated utility lessening the progression of TAO [23]. In the setting of multi-level occlusion the stent puncture technique can help overcome vascular access challenges.…”

Section: Surgical Proceduresmentioning

confidence: 99%

Current Status of Stem Cell Therapy for Thromboangiitis Obliterans (Buerger's Disease)

Peyvandi¹,

Dash²,

Ndon³

et al. 2019

Preprint

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Buerger's disease or Thromboangiitis Obliterans (TAO) is a nonatherosclerotic segmental vascular disease which affects small and medium arteries and veins in the upper and lower extremities. Based on pathological findings, TAO can be considered as a distinct form of vasculitis that is most prevalent in young male smokers. There is no definitive cure for this disease as therapeutic modalities are limited in number and efficacy. Surgical bypass has limited utility and 24% of patients will ultimately require amputation. Recently, studies have shown that therapeutic angiogenesis and immunomodulatory approaches through the delivery of cells to target tissues are potential options for ischemic lesion treatment. In this review, we summarize the current knowledge of TAO treatment and provide an overview of stem cell-based treatment modalities.

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“…Electrical spinal cord stimulation ( 23) is an accepted therapeutic method because of its analgesic effects, the improvement of skin microcirculation in the treated area (13), and the healing of ulcers in severe peripheral atherosclerotic arterial disease (24). The mechanisms behind these effects are still unknown (6,19,23,(25)(26)(27)(28).…”

mentioning

confidence: 99%

Spinal Cord Stimulation in Buerger’s Disease – A Case Report

Santos¹

2019

PMCR

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Buerger’s disease (BD) or thromboangeitis obliterants is a nonatherosclerotic segmental inflammation of the medium- and small-size arteries and vessels of the extremities. The pathogenesis of this process remains unclear. This disease is typically seen in male smokers under 45 years of age, and successful therapy is possible only with abstinence from tobacco. Methods to control ischemic pain include nonpharmacological and pharmacological options, such as prostanoids, or surgical intervention (sympathectomy or revascularization). This case report describes an unusual case of Buerger’s disease in a 60-year-old woman with a moderate smoking habit. Despite apparent tobacco abstinence and therapeutic optimization, there was no clinical improvement in this patient with pharmacological treatment. Attending to the imminent risk of amputation of her fingers, spinal cord stimulation (SCS) system implantation was the chosen therapeutic option. Transcutaneous oxygen pressure (TcPO2) was measured at different points in time after implantation and there was a significant increment of TcPO2 in both hands. In fact, the patient reported no pain after the first month of spinal stimulation; analgesics were progressively reduced and complete healing of ulcers was achieved. Furthermore, the patient reported a substantial improvement in her quality of life and total functional recovery in her hands mobilization after 6 months of treatment. The Brief Pain Inventory Scale and EuroQol- 5D scale were used to evaluate disease progression and its impact on quality of life. SCS system implantation is considered a safe procedure and cost-effective in the long term. The mechanisms behind these effects are still unknown, but SCS is a promising treatment option. More studies that include larger numbers of patients are needed. Key words: Buerger, tobacco, ischemia, amputation, electrical spinal cord stimulation, transcutaneous oxygen pressure

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Treatment of digit ulcers in a patient with Buerger's disease by using cervical spinal cord stimulation -a case report-

Cited by 8 publications

References 13 publications

Spinal cord stimulator for the treatment of ischemic pain-Burger’s Disease and Raynaud’s Disease: A report of 2 cases and literature review

Spinal cord stimulator for the treatment of ischemic pain-Burger’s Disease and Raynaud’s Disease: A report of 2 cases and literature review

Current Status of Stem Cell Therapy for Thromboangiitis Obliterans (Buerger's Disease)

Spinal Cord Stimulation in Buerger’s Disease – A Case Report

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