Treatment of a Patient with Multiple Cutaneous Piloleiomyoma-Related Pain with a Local Injection of Triamcinolone Acetonide

Abstract

Background: Multiple cutaneous piloleiomyomas are rare, frequently painful and difficult-to-treat benign tumours originating in the arrectores pilorum muscles of the hair follicles. Objective: The aim of this study was to determine the efficacy of a local injection of triamcinolone acetonide in relieving cutaneous piloleiomyoma-related pain. Methods: A patient with multiple painful piloleiomyomas was treated with weekly local injections of triamcinolone acetonide into the nodules and papules for 3 weeks. Results: The patient's nodules and papules became smaller, and the pain disappeared. At 1-year follow-up, there were no side effects, pain recurrence or significant enlargement of any of the injected lesions. Conclusion: Our study demonstrates that local injection of triamcinolone acetonide may be a promising new treatment option for multiple painful cutaneous piloleiomyomas.

A Case of Multiple Piloleiomyoma on the Shoulder, which is Mistaken for Keloid

“…We did not use such drugs before the surgery because we could only diagnose the lesions after the biopsy. Some studies have shown that traimacinolone acetonide injections decrease the pain and size of the lesions [13]. However, in our case, the steroid injections that were administered after the patient was misdiagnosed with keloids were not effective, and aaps Archives of Aesthetic Plastic Surgery VOLUME 21.…”

“…Some drugs, for example, nitroglycerin, nifedipine, phenoxybenzamine, and doxazosin, which are effective for inducing smooth muscle contraction, can help reduce pain. Calcium channel blockers, botulinum toxin type A, and antidepressants have recently been used for treatment as well [12,13]. We did not use such drugs before the surgery because we could only diagnose the lesions after the biopsy.…”

An Aggressive Clinical Presentation of Familial Leiomyomatosis Associated with a Fumarate Hydratase Gene Variant of Uncertain Clinical Significance

“…Interestingly, the use of botulinum toxin injection has been reported showing an improvement in pain scores and quality of life ( 12 ). Intralesional triamcinolone also eased pain and reduces the size of the lesions ( 13 ). Topical therapy with capsaicin and topical analgesics has been tried with variable results.…”

Pilar Leiomyoma Located on the Back: A Case Report

“…Destructive methods such as electrodessication, cryotherapy, or carbon-dioxide laser may be employed for small lesions, but there is little known benefit over excision, and unwanted scarring may occur [16,17]. Leiomyoma associated pain can be managed medically with drugs known to affect smooth muscle contraction, such as nitroglycerine, nifedipine, phenoxybenzamine, and doxazosin; recent reports also suggest the use of calcium channel blockers, botulinum toxin type A injections, antidepressants, and triamcinolone acetonide injections [18,19]. For temperature-induced tenderness, gabapentin and topical analgesics, such as lidocaine or capsaicin, may be used [20,21].…”