Treatment Modalities in Adolescents Who Present with Heavy Menstrual Bleeding

Bleeding Disorders in Adolescents with Heavy Menstrual Bleeding: The Queensland Statewide Paediatric and Adolescent Gynaecology Service

“…[25] Management Institution of appropriate long-term management of menses in adolescents with bleeding disorders will be of considerable benefit in preventing morbidity. With mild bleeding disorders causing chronic heavy menstrual bleeding, the combined oral hormonal pill, progesterone only hormonal options, and antifibrinolytics are considered first-line treatment [26,27,28]. In our institution, it would be routine to present all of the hormonal and non-hormonal options, screen for contraindications, and then allow the adolescent and parent/caregiver to make an informed choice after counselling.…”

Recombinant FVIIa therapy for heavy menstrual bleeding in patients with severe FV deficiency

“…8,9 An example of the second approach is the consensus document published by the European Hematology Association (EHA), identifying priorities and needs for haematology research, including haemophilia. 10 A more complex and structured approach is the Delphi process, 11,12 a group communication technique used to gather expert opinion without undue influence from a few dominant stakeholders. 11,13 We report on one such clinical care and research needs assessment, undertaken in a cohort of haemophilia treaters with broad geographical representation.…”

“…[3][4][5][6] Administration of additional hormonal manipulation may be useful in managing bleeding but has not been proven to be optimal treatment for heavy menstrual bleeding. 10 Bypassing-agent monotherapy has been used with variable success in most patients with severe FV deficiency who have inhibitors or are allergic to FFP. [7][8][9] One report describes controlling menstrual bleeding with anti-inhibitor coagulant complex concentrates in such cases; however, this is associated with risk of transmitting viral infection via the plasma product.…”

Trastornos hereditarios de la coagulación en adolescentes con sangrado menstrual excesivo, ¿Debemos evaluar la vía fibrinolítica?

“…Afecta aproximadamente al 40% de las adolescentes 1,9 causando morbilidad y en algunos casos, mortalidad, además de afectar las actividades de la vida diaria, alterando la calidad de vida 4,[10][11][12] . El buen diagnóstico del SME permite establecer medidas activas de manera oportuna para reducir el riesgo de transfusiones, anemia crónica, ausentismo escolar y mejorar calidad de vida [13][14][15][16] .…”