Treatment modalities for molluscum contagiosum

Valentine, Christy L.; Diven, Dayna G.

doi:10.1046/j.1529-8019.2000.00030.x

Cited by 16 publications

(4 citation statements)

References 27 publications

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“…There are many options for treatment of MC and these may be broadly subdivided into destructive, immunological and antiviral therapies. Physical and chemical ablasions are often associated with multiple visits, pain, scarring, postinflammatory changes and frequent recurrences, and these limit the treating of young children 2 . An alternative treatment would be desirable in pediatric patients.…”

Section: The Results From the Imiquimod 5% Cream Treatment Which Was mentioning

confidence: 99%

Topical treatment of molluscum contagiosum with imiquimod 5% cream in Turkish children

Arıcan

2006

Pediatrics International

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When all the patients affected with MC who exclusively used IQ 5% cream as mentioned in the literature were studied, 35 of 83 patients (42.2%) had complete clearance. These have differences in the form and duration of application. IQ 5% cream can be preferred in the treatment of children with MC because of its applicability at home, easy application and good tolerability. However, different application methods and suitable treatment methods should be determined.

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Section: The Results From the Imiquimod 5% Cream Treatment Which Was mentioning

confidence: 99%

Topical treatment of molluscum contagiosum with imiquimod 5% cream in Turkish children

Arıcan

2006

Pediatrics International

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“…Para evitar la incomodidad durante el procedimiento, algunos dermatólogos practican el raspado de las lesiones bajo anestesia tópica o, en niños pequeños con abundantes lesiones, bajo anestesia general. En algunos estudios también se reporta la utilidad de la terapia láser en las lesiones de molusco contagioso, con buenos resultados, teniendo en cuenta la edad del paciente, el número y la localización de las lesiones (20,(22)(23) . En un estudio, se analizaron la eficacia y los efectos secundarios de cuatro tratamientos en 124 niños (19) .…”

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Molusco contagioso

Rodríguez¹,

Arenas²

2017

rev. asoc. colomb. dermatol. cir. dematol.

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El molusco contagioso afecta entre el 5 y el 16 % de los niños menores de 16 años, principalmente aquellos con dermatitis atópica. Es frecuente en pacientes inmunosuprimidos, especialmente aquellos con sida. Se manifiesta como pápulas eucrómicas, umbilicadas, pequeñas, localizadas frecuentemente en la cara y los pliegues. Se transmite por contacto directo con la piel o por fómites y, en los niños, se presenta autoinoculación. En pacientes con sida, las lesiones pueden alcanzar gran número y tamaño, y ser de mayor duración y recurrentes. El diagnóstico es clínico, pero en casos de duda, el frotis directo o la biopsia son concluyentes. El tratamiento del molusco contagioso es diverso y depende de la experiencia de cada profesional. El objetivo de esta revisión de tema es recordar las principales características de esta infección, algunas propiedades del virus y su desarrollo en los queratocitos epidérmicos. También, se hace un resumen de las principales opciones terapéuticas disponibles para su manejo.

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“…Evisceration: An easy method to remove the lesions is eviscerating the core with an instrument such as a scalpel, sharp tooth pick, edge of glass slide, or any other instrument capable of removing the umbilicated core. This method may not be tolerated by small children [34,35].…”

Section: Nitric Oxide Creammentioning

confidence: 99%

Treatment of Molluscum Contagiosum by Potassium Hydroxide Solution 20% with and Without Pricking and By Pricking Alone: A Comparative Study with Review of Literature

Maluki¹

2015

Int J Dermatol Clin Res

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Background: Molluscum Contagiosum is a common viral skin infection, caused by poxvirus, commonly affects young children. Although there is no specific treatment for this infection, many therapeutic modalities has been used with different success rates. Objectives: To evaluate the effectiveness of topical 20% KOH, 20% KOH with pricking and pricking alone as comparative treatments for molluscum contagiosum. Patients and methods: This study was conducted in the Dermatology Clinic of Kufa Medical School Teaching Hospital in Iraq, from August 2011 to January 2013. Ninety patients with Molluscum Contagiosum were recruited. Diagnosis of Molluscum Contagiosum was confirmed on clinical bases. Patients with prior treatment for the last month and patients who had inflamed lesions were excluded. Full history and physical examination were done for all Patients. The patients were divided into three groups: Group 1included 30 patients treated with topical KOH 20% applied by wooden stick daily at bed time. Group 2 included 30 patients treated by pricking the lesions by 27 G needle wet in 20% KOH weekly. Group 3 included 30 patients treated by pricking alone once weekly. Treatment sessions were continued until complete cure or maximum of four sessions was achieved. The patients were followed up for two months period from the last session. Results: Out of the ninety patients, 57 completed the study. There were thirty one (54.3%) males and 26 (45.6%) females with male to female ratio 1.19-. Their ages ranged from 1.5-62 years (mean and standard deviation of 19.4±16.7). The most common age group affected was below 12 years, 29 (50.8%) patients. The most commonly affected body sites were the face and neck, 49 (85.9%) patients. After 4 sessions, the response rate was as follows:-Group 1, 17 (94.4%): patients were cured completely and relapse was not recorded; p-value was highly significant (=0.0019).-Group 2, 20 (86.4%) patients were completely cured and relapse was not recorded; p-value was highly significant (< 0.001).-Group 3, 12 (75%) patients were completely cured and relapse was not recorded; p-value was highly significant (=0.0014). Conclusion: Pricking Molluscum Contagiosum by 27G needle alone, pricking with 20% KOH and topically applied 20% KOH all achieved comparable success rates that were all statistically significant. All three methods represented tolerable and highly effective modes of therapy. Historical review: MC was first described and later assigned its name by Bateman in the beginning of the Nineteenth Century. In 1841, Henderson and Paterson described the intracytoplasmic inclusion bodies now known as Molluscum or Henderson-Paterson bodies. In the early Twentieth Century, Julinsberg, Wile and Kingery were able to extract filterable virus from lesions and show transmissibility. Goodpasture later described the similarities of Molluscum and vaccinia [2].

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Treatment modalities for molluscum contagiosum

Cited by 16 publications

References 27 publications

Topical treatment of molluscum contagiosum with imiquimod 5% cream in Turkish children

Topical treatment of molluscum contagiosum with imiquimod 5% cream in Turkish children

Molusco contagioso

Treatment of Molluscum Contagiosum by Potassium Hydroxide Solution 20% with and Without Pricking and By Pricking Alone: A Comparative Study with Review of Literature

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