Traumatic Ulcerative Granuloma With Stromal Eosinophilia – Case Series

Abstract

Traumatic ulcerative granuloma with stromal eosinophilia (TUGSE) is relatively uncommon lesion presenting clinically as ulceration of the oral mucosa with a chronic course associated with delayed healing. Chronic irritation causing trauma to the oral mucosa is considered as major causative factor. The most commonly affected site of the lesion appears to be Tongue and Buccal mucosa. This lesion represents clinically as ulcer with indurated margins mimicking malignancy, causing diagnostic challenge for the dentists. Histologically characterized by breach in the epithelium exposing underlying connective tissue inltrated with dense amount of inammatory cells predominantly of eosinophils penetrating the underlying mucle. It is important to diagnose the lesion histologically to rule out malignancy and to treat appropriately. However the lesion resolves on its own or with minimal and conservative treatment. In this review we present four case series of clinically manifesting ulceroproliferative lesions on buccal mucosa and diagnosed as TUGSE,based on clinical and histopathological features.