Tratamento farmacológico das psicoses na epilepsia

Guarnieri, Ricardo; Hallak, Jaime Eduardo Cecílio; Walz, Roger; Velasco, Tonicarlo Rodrigues; Júnior, Veriano Alexandre; Wichert‐Ana, Lauro; Sakamoto, Américo Ceiki

doi:10.1590/s1516-44462004000100014

Cited by 13 publications

(7 citation statements)

References 31 publications

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“…However, among the atypical antipsychotics, clozapine is the most epileptogenic with seizures being reported in 0.3% to 5% of people treated with therapeutic doses. Similarly, olanzapine has also showed occurrence of seizure in 0.24% of patients without epilepsy [15]. Incidence of seizure is more likely if the dose of olanzapine exceeds 20mg, especially in individuals with epilepsy, according to Degner et al [16].…”

Section: Discussionmentioning

confidence: 99%

A Case of Complex Partial Seizures Presenting as Acute and Transient Psychotic Disorder

Sultan

Fallata

2019

Case Reports in Psychiatry

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Introduction. Complex partial seizures are focal (CPS) (i.e., start in one area of the brain) and associated with impairment in consciousness. Most of them arise in the temporal region and are characterized by aura, impaired consciousness, and automatisms. CPS that arise in temporal region are most often misdiagnosed as primary psychiatric illness. Case Report. A 25-year-old male presented with fluctuations in consciousness, aggressive behaviour, hallucination, and delusions of grandeur lasting a few hours. He was diagnosed with acute and transient psychotic disorder according to ICD10 criteria and was treated with intramuscular haloperidol 10mg BID followed by oral olanzapine 10mg. Computed tomography of brain and electroencephalogram were normal. After 15 days he presented again to the outpatient department with complaints of aggressive behaviour and sensory misinterpretations. Video electroencephalogram was recommended, which was not done due to financial constraints. The diagnosis was reconsidered and he was started on oral carbamazepine due to high clinical suspicion, of complex partial seizures, in spite of lack of EEG evidence. He responded well to antiepileptic and symptom remission has maintained well. Conclusion. Patients presenting with psychosis need careful diagnostic evaluation for other possibilities.

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Section: Discussionmentioning

confidence: 99%

A Case of Complex Partial Seizures Presenting as Acute and Transient Psychotic Disorder

Sultan

Fallata

2019

Case Reports in Psychiatry

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“…Haloperidol has best antipsychotic action without decreasing epileptogenic threshold. 2 It is indicated mainly for acute and severe psychotic states that require rapid onset of action for a short time period.…”

Section: Antipsychotic Treatmentmentioning

confidence: 99%

“…2 Despite many available treatment options, almost 30% of epilepsy patients still continue to have seizures. 3 Deep brain stimulation technique is being investigated as a prospective epilepsy treatment.…”

Section: Antipsychotic Treatmentmentioning

confidence: 99%

Status Epilepticus and Psychosis of Epilepsy

Hasija¹,

Jadapalle²,

Badr³

2012

Psychiatric Annals

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“…47 Transtornos psicóticos interictais, principalmente os recorrentes ou de curso crônico, têm sido estudados de maneira mais persistente, por servirem como um modelo para o estudo da esquizofrenia. Os episódios psicóticos em geral se iniciam de maneira insidiosa, cursam com delírios (em muitos casos religiosos ou místicos, de perseguição e/ou de referência), alucinações, transtorno de pensamento (inabilidade de lidar com conceitos complexos, divagação, circunstancialidade, mas também um transtorno de pensamento mais tipicamente esquizofrênico com bloqueio de pensamento, neologismos e sintaxe perturbada), comportamento desorganizado, ausência relativa de sintomas catatônicos, oscilações de humor transitórias e intensas (mais freqüentemente de humor depressivo e ou irritável), apragmatismo e embotamento afetivo (menos intenso do que o observado na esquizofrenia clássica, com preservação relativa do calor afetivo e da capacidade para relações sociais).…”

Section: Psicose E Epilepsiaunclassified

Aspectos epidemiológicos e relevância dos transtornos mentais associados à epilepsia

Neto

Marchetti

2005

Rev. Bras. Psiquiatr.

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Aspectos epidemiológicos e relevância dos transtornos mentais associados à epilepsia Epidemiologic aspects and relevance of mental disorders associated with epilepsyResumo Epilepsia é o mais freqüente transtorno neurológico sério, atingindo 50 milhões de pessoas no mundo, 40 milhões delas em países em desenvolvimento. Embora seja um problema predominantemente tratável, nestes países a maioria dos pacientes permanece sem tratamento. Provavelmente, uma das principais causas para isto seja o estigma que atinge as pessoas com epilepsia. Tal fato se agrava ainda mais quando à epilepsia se associam os transtornos mentais, que ocorrem com prevalência aumentada. Os pacientes com epilepsia e transtornos mentais sofrem o que chamamos de "duplo estigma", que freqüentemente os deixa sem tratamento. É provável, particularmente em países em desenvolvimento, que psiquiatras se defrontem com pacientes com epilepsia nos diferentes locais de atendimento. O presente estudo tem como objetivo revisar a epidemiologia dos transtornos mentais associados à epilepsia, determinando a lacuna de tratamento e o impacto destes transtornos na qualidade de vida dos pacientes.Descritores: Epilepsia/epidemiologia; Transtornos mentais/epidemiologia; Saúde pública; Efeitos psicossociais da doença; Qualidade de vida A b s t r a c t Epilepsy is the most common serious neurological disorder. Worldwide, around 50 million people have epilepsy, 40 million of which in developing countries. Though epilepsy is predominantly treatable, most patients in these countries remain without treatment. It is likely that one of the main reasons is the stigma associated with epilepsy. This problem increases when mental disorders are associated with epilepsy, a fairly frequent occurrence. Patients with epilepsy and mental disorders are exposed to a "double stigma", which frequently leads to complete absence of treatment. It is probable that, particularly in developing countries, psychiatrists will be involved with the treatment of people with epilepsy. Our purpose was to review the epidemiology of mental disorders associated with epilepsy, its treatment gap and impact upon quality of life of the patients.

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Tratamento farmacológico das psicoses na epilepsia

Cited by 13 publications

References 31 publications

A Case of Complex Partial Seizures Presenting as Acute and Transient Psychotic Disorder

A Case of Complex Partial Seizures Presenting as Acute and Transient Psychotic Disorder

Status Epilepticus and Psychosis of Epilepsy

Aspectos epidemiológicos e relevância dos transtornos mentais associados à epilepsia

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