2011
DOI: 10.1038/ncomms1480
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Trapping and rotating nanoparticles using a plasmonic nano-tweezer with an integrated heat sink

Abstract: Although optical tweezers based on far-fields have proven highly successful for manipulating objects larger than the wavelength of light, they face difficulties at the nanoscale because of the diffraction-limited focused spot size. This has motivated interest in trapping particles with plasmonic nanostructures, as they enable intense fields confined to sub-wavelength dimensions. A fundamental issue with plasmonics, however, is ohmic loss, which results in the water, in which the trapping is performed, being he… Show more

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Cited by 404 publications
(413 citation statements)
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“…Although optical tweezers have demonstrated excellent precision and versatility for a number of functionalities, they have two potential shortcomings: First, they may cause physiological damage to cells and other biological objects from potential laser-induced heating, multiphoton absorption in biological materials, and the formation of singlet oxygen (8); and second, they rely on complex, potentially expensive optical setups that are difficult to maintain and miniaturize. Many alternative bioparticle-manipulation techniques (9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22) have since been developed to overcome these shortcomings, however, each technique has its own potential drawbacks. For example, magnetic tweezers (17)(18)(19) require targets to be prelabeled with magnetic materials, a procedure that affects cell viability; electrophoresis/dielectrophoresis based methods (9)(10)(11)(20)(21)(22) are strictly dependent on particle polarizibility and medium conductivity and utilize electrical forces that may adversely affect cell physiology due to current-induced heating and/or direct electricfield interaction (23).…”
mentioning
confidence: 99%
“…Although optical tweezers have demonstrated excellent precision and versatility for a number of functionalities, they have two potential shortcomings: First, they may cause physiological damage to cells and other biological objects from potential laser-induced heating, multiphoton absorption in biological materials, and the formation of singlet oxygen (8); and second, they rely on complex, potentially expensive optical setups that are difficult to maintain and miniaturize. Many alternative bioparticle-manipulation techniques (9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22) have since been developed to overcome these shortcomings, however, each technique has its own potential drawbacks. For example, magnetic tweezers (17)(18)(19) require targets to be prelabeled with magnetic materials, a procedure that affects cell viability; electrophoresis/dielectrophoresis based methods (9)(10)(11)(20)(21)(22) are strictly dependent on particle polarizibility and medium conductivity and utilize electrical forces that may adversely affect cell physiology due to current-induced heating and/or direct electricfield interaction (23).…”
mentioning
confidence: 99%
“…[42][43][44] Excessive photothermal heating may adversely affect the microbial growth, and must be controlled, for example, by engineering proper heat-sinks. 45 The work reported here represents a significant step toward these goals.…”
Section: Discussionmentioning
confidence: 97%
“…One such application is metal enhanced fluorescence imaging [10] of molecules at low concentrations where few fluorophores are available per unit volume, and a large interaction volume would be preferred to improve the measured signal.…”
Section: Discussionmentioning
confidence: 99%
“…1 are considered. Such tubular plasmonic structures have been used, e.g., as high performance biosensors (see, e.g., [9]) or as field concentrators for trapping of nanoparticles [10]. We restrict our discussion to isolated structures rather than arrays and also focus on fabrication methods such as ISL, which generate a distribution of diameters rather than a single size.…”
Section: Introductionmentioning
confidence: 99%