Transurethral „En Bloc“ Resection Technique In Non-Muscle Invasive Bladder Cancer

Vladanov, Ivan; Plesacov, Alexei; Colta, Artur; Ceban, Emil; Ghicavii, Vitalii; Scutelnic, Ghenadie

doi:10.31688/abmu.2020.55.2.07

Cited by 2 publications

(1 citation statement)

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“…According to our inclusion criteria, we finally identified 29 studies comprising 4,484 patients for meta-analysis. 9–16,24,25,29,36–50,51–53 Of 29 included studies, 13 RCTs comprising 1,792 patients were eligible for analysis of oncologic and perioperative outcomes, 9–16,36–40 and 5 RCTs and 16 NRCTs/observational studies comprising 3,369 patients were eligible for analysis of pathological and reTUR outcomes. 10–13,24,25,29,40–50,51–53 The demographics of each included study are represented in tables 1 and 2.…”

Section: Resultsmentioning

confidence: 99%

En Bloc Resection for Bladder Tumors: An Updated Systematic Review and Meta-Analysis of Its Differential Effect on Safety, Recurrence and Histopathology

et al. 2022

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Purpose: En bloc resection for bladder tumors has been developed to overcome shortcomings of conventional transurethral resection of bladder tumors with regard to safety, pathological evaluation and oncologic outcomes. However, the potential benefits and utility compared to conventional transurethral resection of bladder tumors have not been conclusively demonstrated. We aimed to update the current evidence with focus on the pathological benefits of en bloc resection for nonmuscle-invasive bladder cancer. Materials and Methods: The PubMedÒ, Web of ScienceÔ and ScopusÒ databases were searched in August 2021 according to the PRISMA (Preferred Reporting Items for Systematic Review and Meta-Analyses) statement. Studies were deemed eligible if they compared safety, and pathological and clinical outcomes in patients who underwent en bloc resection with conventional transurethral resection of bladder tumors.

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Section: Resultsmentioning

confidence: 99%

En Bloc Resection for Bladder Tumors: An Updated Systematic Review and Meta-Analysis of Its Differential Effect on Safety, Recurrence and Histopathology

et al. 2022

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Comparison of Pathological Outcome and Recurrence Rate between En Bloc Transurethral Resection of Bladder Tumor and Conventional Transurethral Resection: A Meta-Analysis

Wang¹,

Lee²,

Wu³

et al. 2023

Cancers

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Current treatment for non-muscle invasive bladder cancer (NMIBC) is the conventional transurethral resection of bladder tumor (CTURBT), but the en bloc transurethral resection of bladder tumor (ERBT) has been gaining more attraction in recent years considering better specimen integrity. Thus, we conducted this meta-analysis to compare the safety and efficacy of ERBT versus CTURBT. Trials were collected from an online database. The primary outcomes included identification of detrusor muscle in specimen, residual tumor, 3, 12, and 24-month recurrence rates and same-site recurrence rate. A total of 31 trials were included. The ERBT group had a higher rate of identification of detrusor muscle in specimens (p = 0.003) and lower residual tumor (p < 0.001). Other than that, lower rates of 3-month (p = 0.005) and 24-month recurrence rate (p < 0.001), same-site recurrence rate (p < 0.001) and complications were also observed. For perioperative outcomes, shorter hospitalization time (HT) (p < 0.001), and catheterization time (CT) (p < 0.001) were also revealed in the ERBT group. No significant difference was found in operative time (OT) (p = 0.93). The use of ERBT showed better pathological outcomes and fewer complications, so it could be considered a more effective treatment option for NMIBC.

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Transurethral „En Bloc“ Resection Technique In Non-Muscle Invasive Bladder Cancer

Cited by 2 publications

References 0 publications

En Bloc Resection for Bladder Tumors: An Updated Systematic Review and Meta-Analysis of Its Differential Effect on Safety, Recurrence and Histopathology

En Bloc Resection for Bladder Tumors: An Updated Systematic Review and Meta-Analysis of Its Differential Effect on Safety, Recurrence and Histopathology

Comparison of Pathological Outcome and Recurrence Rate between En Bloc Transurethral Resection of Bladder Tumor and Conventional Transurethral Resection: A Meta-Analysis

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