“…Pellicore et al observed bone growth stimulation following amputation and concluded that stump overgrowth occurs because soft tissues cannot keep up with the rapid growth of the bone [16]; however, attempts to treat overgrowth by proximal epiphysiodesis and leaving long redundant soft tissue have failed [12,[17][18][19]. The incidence of the overgrowth phenomenon in cases of surgical and post-trauma amputations was higher [1][2][3]5] compared with that of disarticulation amputation and congenital agenesis, [7,20] which suggests that stump overgrowth might be a result of bone and soft tissue trauma rather than continuous growth of the proximal physis. This would mean that overgrowth is a local Stump Overgrowth after Limb Amputation in Children DOI: http://dx.doi.org /10.5772/intechopen.90532 process of bone formation and wound healing that occur in the distal stump.…”
Stump overgrowth is the most common complication after limb amputation in children. Its morbidity is relatively high, that required frequent revisions of the stump and prosthesis. The incidence of stump overgrowth varies in the literature; depending on different factors. The exact pathogenesis is unclear, many hypotheses have been suggested. The treatment is a challenge; simple excision of the bone is associated with recurrence and further shorting of the stump. Many options of treatment have been used. This paper is an up-to date literature review that includes the definition, incidence, pathogenesis, clinical presentation, radiographic diagnosis, and treatment options of stump overgrowth in children.
“…Pellicore et al observed bone growth stimulation following amputation and concluded that stump overgrowth occurs because soft tissues cannot keep up with the rapid growth of the bone [16]; however, attempts to treat overgrowth by proximal epiphysiodesis and leaving long redundant soft tissue have failed [12,[17][18][19]. The incidence of the overgrowth phenomenon in cases of surgical and post-trauma amputations was higher [1][2][3]5] compared with that of disarticulation amputation and congenital agenesis, [7,20] which suggests that stump overgrowth might be a result of bone and soft tissue trauma rather than continuous growth of the proximal physis. This would mean that overgrowth is a local Stump Overgrowth after Limb Amputation in Children DOI: http://dx.doi.org /10.5772/intechopen.90532 process of bone formation and wound healing that occur in the distal stump.…”
Stump overgrowth is the most common complication after limb amputation in children. Its morbidity is relatively high, that required frequent revisions of the stump and prosthesis. The incidence of stump overgrowth varies in the literature; depending on different factors. The exact pathogenesis is unclear, many hypotheses have been suggested. The treatment is a challenge; simple excision of the bone is associated with recurrence and further shorting of the stump. Many options of treatment have been used. This paper is an up-to date literature review that includes the definition, incidence, pathogenesis, clinical presentation, radiographic diagnosis, and treatment options of stump overgrowth in children.
“…If we can impart a greater potential of these periosteal cells to proliferate to a similar extent to that of the PP cells through a means of dedifferentiation/reprogramming (Takahashi and Yamanaka, 2006) or transdifferentiation (Thorel et al, 2010), we might be able to realize the dream of regenerating limbs in humans. Indeed, an overgrowth of bone over the limb stump sometimes occurs in subjects after an amputation transects the long bone (Firth et al, 2011). This phenomenon occurs most commonly in children under 12 years of age, but never after a person reaches skeletal maturity, which indicates that as long as the periosteal cells of the long bone possess the ability to proliferate, they would be able to extend a stump further.…”
Section: Lessons Learnt From Antler For Regenerative Medicinementioning
“…Data is limited, and results have been mixed. 19,20 Firth and colleagues treated four patients with the Ertl procedure. One of the four cases required revision for stump overgrowth.…”
Although many of the surgical and technological advances for prosthetics have emerged from caring for adults, the pediatric patient with limb differences continues to provide unique challenges and demands appropriate, pediatric-specific innovation. Not only do children test the current technology with their size, weight, and potential growth, but also with their chosen activities, energy-level and drive to explore varied environments. This article explores the recent advances within the broader realm of prosthetics, primarily based on research in adult patients. It identifies technologies that have already been translated to pediatric populations and points out areas for potential pediatric applications. This review also highlights numerous needs and gaps in the currently available resources and tools for these patients, including surgical techniques, prosthetic componentry, and rehabilitation strategies. Further innovation and research are needed for pediatric patients to maximize their functional potential while using a prosthesis.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.