Transplantation utérine : une demande réelle ?

Options for acquiring motherhood in absolute uterine factor infertility; adoption, surrogacy and uterine transplantation

“…Another study, specifically assessing perceptions in women with MRKH, showed that almost two‐thirds of participants were motivated to undergo UTx, even after becoming aware of the associated risks 79 . This is similar to the findings of a questionnaire in 60 women with AUFI in France, which found that 58.3% would partake in a UTx clinical trial 80 …”

“…79 This is similar to the findings of a questionnaire in 60 women with AUFI in France, which found that 58.3% would partake in a UTx clinical trial. 80 Given the additional risks associated with UTx, current selection criteria for a continuing UK research trial using deceased donors (Investigational Study Into Transplantation of the Uterus; INSITU) ensure recipients are aged 24-38, have a BMI <30 kg/m 2 and normally functioning ovaries. 81 Exclusion criteria include already having children, poor fitness and health or significant medical or psychiatric comorbidity, major or multiple previous abdominal surgery, or severe endometriosis.…”

Intra- and Postoperative Blood Flow Monitoring in a Sheep Model of Uterus Transplantation

“…It can be said with certainty that uterus transplantation in humans is still at an early stage. Nevertheless, in a previous survey by Gauthier et al, 35 out of 60 women suffering from uterine infertility were willing to undergo uterus transplantation, accepting the uncertainty of the outcome and the attendant risks, most likely due to the extreme psychological stress associated with infertility (27). As surgeons, we carry a major share of the responsibilities: Comprehensive preparation is of utmost importance.…”

Human Uterus Transplantation: Have We Opened a Pandora’s Box?

“…Gauthier et al sent anonymous questionnaires to associations of patients with Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome and to women suffering from AUFI devised to sound out their attitude toward uterine transplantation and toward adoption and gestational surrogacy [15]. Sixty patients answered the questionnaire.…”