Transplantation of a lobe of the liver in the rat

Seneviratne, R. D.

doi:10.1002/path.1700700202

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1999

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Cited by 6 publications

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“…The ultimate fate of liver grafts, placed in the anterior chamber of the eye, mesotestis, peritoneum, subcutaneous tissue, etc. has been atrophy and degeneration, secondary to lack of blood supply and to pressure nec rosis, due to proliferation of bile ducts following transplantation [2,3,4,5,7,9,12], In view of the remarkable regenerating ability of liver, success in es tablishing an intact and functioning portion in an heterotopic location could open new vistas for clinical application and does provide a method for study of liver regeneration in experimental animals.…”

Section: Technique Materials Methodsmentioning

confidence: 99%

DNA and Protein Metabolism After Liver Autotransplantation

Tamvakopoulos¹,

Randall²,

VanLancker³

1969

Eur Surg Res

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Section: Technique Materials Methodsmentioning

confidence: 99%

DNA and Protein Metabolism After Liver Autotransplantation

Tamvakopoulos¹,

Randall²,

VanLancker³

1969

Eur Surg Res

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Hepatocyte transplantation: Back to the future

Gupta

Chowdhury

1992

Hepatology

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Hepatocelluläre Transplantation – von den Anfängen bis zum klinischen Einsatz

Markus

Becker

1999

Chirurg

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Within the past 30 years hepatocyte transplantation has been developed in rodents for the cure of acute and chronic liver failure. Organ shortage and the enormous costs of orthotopic liver transplantation have promoted intensive research in transplantation of isolated hepatocytes. Transplanted syngeneic hepatocytes survive indefinitively in rodents, allowing correction of various inherited liver enzyme defects or enhancing recipient survival in experimentally induced acute liver failure. The clinical application of hepatocyte transplantation has been recently demonstrated in a young patient suffering from Crigler-Najjar syndrome type I, with successful long-term survival of allogeneic hepatocytes. This review reports the historical development and the published data on experimental and clinical hepatocyte transplantation.

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Transplantation of a lobe of the liver in the rat

Cited by 6 publications

References 12 publications

DNA and Protein Metabolism After Liver Autotransplantation

DNA and Protein Metabolism After Liver Autotransplantation

Hepatocyte transplantation: Back to the future

Hepatocelluläre Transplantation – von den Anfängen bis zum klinischen Einsatz

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