Transplantation for Myocarditis: A Controversy Revisited

Moloney, E; Egan, Jim; Kelly, Peter; Wood, A. E.; Cooper, Leslie T.

doi:10.1016/j.healun.2004.06.015

Cited by 50 publications

(23 citation statements)

References 47 publications

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“…Although pediatric myocarditis is generally associated with improvement in and resolution of cardiac dysfunction, a substantial minority of patients (Figures 1 and 3) will have recalcitrant heart failure unresponsive to medical management that leads to heart transplantation. Outcomes for adult 146 and pediatric 147 heart transplantation have been reported to be similar to results for transplantation with other cardiomyopathies. Within the Pediatric Heart Transplant Study (PHTS) database, the 10-year survival rate after heart transplantation for dilated cardiomyopathy is ≈70%.…”

Section: Diagnosis and Therapy For Myocarditis In Children 123mentioning

confidence: 69%

Diagnosis and Treatment of Myocarditis in Children in the Current Era

2014

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Section: Diagnosis and Therapy For Myocarditis In Children 123mentioning

confidence: 69%

Diagnosis and Treatment of Myocarditis in Children in the Current Era

2014

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“…[8][9][10] We, therefore, sought to use a large, contemporary, nationwide database to better understand the clinical characteristics, natural history, MCS needs, and HT outcomes of patients with end-stage HF from myocarditis listed for HT.…”

Section: See Clinical Perspectivementioning

confidence: 99%

Characteristics and Outcomes of Patients With Myocarditis Listed for Heart Transplantation

ElAmm

Al‐Kindi

Oliveira

2016

Circ: Heart Failure

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Background-Myocarditis can cause dilated cardiomyopathy resulting in end-stage heart failure requiring advanced therapies. There is little contemporary information on the clinical progression, need for mechanical circulatory support, and outcomes of orthotopic heart transplantation of these patients. Despite higher allosensitization, patients with myocarditis had similar post-transplant rejection, retransplantation, and survival rates compared with other groups. Conclusions-Patients with the diagnosis of myocarditis listed for orthotopic heart transplantation are younger, sicker, and recover more frequently but require more biventricular mechanical circulatory support. Heart transplantation survival is comparable to that of patients with other types of heart failure. (Circ Heart Fail. 2016;9:e003259. Methods and Results-We

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“…Myocarditis is a major cause of end-stage heart failure and is responsible for up to 10% of cases of idiopathic dilated cardiomyopathy (DCM) [1]. However, the etiology of myocarditis remains unclear and no effective treatment for humans has been established.…”

Section: Introductionmentioning

confidence: 99%