“…Drug was detected in fetal urine for up to 20 h after the dose, but no antimicrobial activity at any time could be demonstrated in fetal CSF, fetal lung, fetal liver, or fetal kidney. DEKEL et al (1980) reports that cefazolin crosses the placenta more easily during the second and third trimesters of pregnancy than during the first. Similar studies have been conducted by VON KOBYLETZKI et al (1974).…”