Transphenoidal endoscopic approaches for pituitary adenomas: a critical review of our experience

Characteristics and outcome of surgically treated pituitary tumours in South Africa: a single‐centre experience

“…11,25,27 The role of surgery in such cases remains to remove as much tumour as possible with minimum morbidity to permit easier control of tumour growth by adjuvant therapies, as complete removal is unlikely in patients with large tumours. 24 The finding that there was a high proportion (47Á1%) of NFPA is consistent with other studies which report NFPA in 51Á3-84% 2,16,27 but in contrast to other studies which report rates of 28Á5%. 28 It is well known that immunohistochemical analysis of NFPAs reveals that a significant proportion of these tumours do in fact synthesize pituitary hormones despite the absence of a clinically apparent endocrine hypersecretion syndrome.…”

“…[19][20][21][22] By contrast, in other studies, macroadenomas represented the majority (92-97%). 23,24 Consistent with available literature, 12,13 TSS was the most frequently employed approach (81Á4%) at our institution. Only 10% initially had trans-cranial surgery, and 8Á6% needed to undergo both approaches.…”

“…From available reports, the findings of tumour size at presentation have been variable; some studies have reported that microadenomas predominate with macroadenomas accounting for only 0·16–10·4% . By contrast, in other studies, macroadenomas represented the majority (92–97%) …”

“…(20%) . The role of surgery in such cases remains to remove as much tumour as possible with minimum morbidity to permit easier control of tumour growth by adjuvant therapies, as complete removal is unlikely in patients with large tumours …”

Endoscopic endonasal trans-sphenoid surgery of pituitary adenoma

“…[66] Endoscopic pituitary surgery was found to be safe. [51,[67][68][69] The quality life was better in terms of patient discomfort and pain perception [70][71][72][73] as compared to conventional microscopic technique. Operating time, [71,[74][75][76][77] hospital stay, [71,72,74,[76][77][78] and blood loss [72][73][74]77] was less in the endoscopic technique as compared to the microscopic technique.…”