Transoral Carbon Dioxide Laser Supraglottic Laryngectomy and Irradiation in Stage I, II, and III Squamous Cell Carcinoma of the Supraglottic Larynx

Agrawal, Amit; Moon, James; Davis, R. Kim; Sakr, Wael; Giri, Shankar; Valentino, Joseph; LeBlanc, Michael; Truelson, John M.; Yoo, George H.; Ensley, John F.; Schuller, David E.

doi:10.1001/archotol.133.10.1044

Cited by 36 publications

(25 citation statements)

References 19 publications

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“…3,5,[11][12][13][14] In addition, TLM has repeatedly demonstrated cure rates for supraglottic cancer comparable with those of open surgery or primary radiotherapy. 5,6,7,[11][12][13][14]17 This therapeutic effectiveness has been confirmed by the present study.…”

Section: Discussionsupporting

confidence: 90%

Evaluation of available surgical management options for early supraglottic cancer

et al. 2009

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Section: Discussionsupporting

confidence: 90%

Evaluation of available surgical management options for early supraglottic cancer

et al. 2009

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“…nevertheless, long-term results are similar whether transoral or open surgery is performed [8,12]. In our sample, nasogastric feeding was necessary in 13 patients (24 %), most of whom required it for less than 10 days postoperatively, with only one patient needing it for 90 days due to chronic aspiration pneumonia.…”

Section: Swallowingmentioning

confidence: 58%

“…Agrawal [8] described only one patient with local disease recurrence that required total laryngectomy. Vilaseca [9] reported 37.5 % of local recurrences, which were treated by laser surgery in five patients, partial external surgery in five, and total laryngectomy in 45.…”

Section: Discussionmentioning

confidence: 99%

“…Two of the four tracheotomies were closed and the incidence of permanent tracheotomy was 8 %, similar to that of our patients (7.4 %). Agrawal [8] reviewed 34 cases of supraglottic cancer (T1-T2-n0-n1) that were treated with transoral supraglottic laryngectomy followed by postoperative radiotherapy, and only four patients underwent tracheostomy during the initial surgical procedure, all as a consequence of either obstructing tumours or unfavourable anatomy that precluded safe intubation.…”

Section: Tracheostomy and Decannulationmentioning

confidence: 99%

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Transoral resection of supraglottic tumours using microelectrodes (54 cases)

Basterra

Esteban

Reboll

et al. 2014

Eur Arch Otorhinolaryngol

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We present the oncological and functional results of surgical transoral resection of supraglottic laryngeal carcinomas using microelectrodes. This prospective multicentre trial was conducted from 2005 to 2009. It included 54 patients (23 T1, 14 T2, and 17 T3) with supraglottic cancer, with a follow-up of 2 years. Outcome measurements were: tracheostomy, hospital stay, nasogastric feeding and recurrences. Four patients required permanent tracheostomies. The mean hospital stay was 8.1 days. Temporary nasogastric feeding was necessary in 13 patients. Postoperative complications included two incidences of haemorrhage requiring surgical intervention and one pneumonia. Four patients out of eight with T3 tumours had regional recurrence; in these cases salvage surgery was performed: two cases by the transoral approach and six total laryngectomies. Clinical results were similar to those obtained with CO2 laser therapy. We list other advantages of the technique and include a literature review.

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“…The second is to perform an external surgery due to the need for bilateral neck dissection. In tumors that are endoscopically accessible, while TLM has similar local control and survival rates compared to open supraglottic laryngectomy, its functional outcomes are more satisfying (22,23). In addition, when TLM is combined with postoperative RT in the neck, it provides high rates of local control and survival (88% for three years) (23).…”

Section: Clinical and Research Impactsmentioning

confidence: 99%

Minimally Invasive Procedures for Laryngeal Carcinoma: Transoral Endoscopic Laser and Transoral Robotic Surgery

Topal¹

2017

Turk Arch Otorhinolaryngol

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Open partial or total laryngectomies with or without radiotherapy (RT) or chemoradiotherapy (CRT) are the only mainstays in the treatment of laryngeal carcinomas. However, minimally invasive procedures such as transoral endoscopic carbondioxide laser microsurgery (TLM) or transoral robotic surgeries (TRS) are now being increasingly used in selected patients. The laryngeal framework is not disturbed in these procedures; therefore, the postoperative swallowing function improves more rapidly, and routine tracheotomy is not usually required. Moreover, they have oncological results comparable with open procedures.

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Transoral Carbon Dioxide Laser Supraglottic Laryngectomy and Irradiation in Stage I, II, and III Squamous Cell Carcinoma of the Supraglottic Larynx

Abstract: To evaluate feasibility, functional outcome, and disease control of endoscopic surgery and irradiation in patients with squamous cell carcinoma of the supraglottic larynx.

Cited by 36 publications

References 19 publications

Evaluation of available surgical management options for early supraglottic cancer

Evaluation of available surgical management options for early supraglottic cancer

Transoral resection of supraglottic tumours using microelectrodes (54 cases)

Minimally Invasive Procedures for Laryngeal Carcinoma: Transoral Endoscopic Laser and Transoral Robotic Surgery

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