Evaluation of available surgical management options for early supraglottic cancer

Karatzanis, Alexander D.; Psychogios, Georgios; Zenk, Johannes; Waldfahrer, Frank; Hornung, Joachim; Velegrakis, George A.; Iro, Heinrich

doi:10.1002/hed.21289

Cited by 35 publications

(45 citation statements)

References 30 publications

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“…The functional results after transoral laser surgery of supraglottic carcinomas are good, permanent tracheostomy and functional laryngectomy as well as permanent PEG are rare [16], [53], [56], [57]. Ambrosch et al [16] reported about 2% permanent tracheostomies in a population of 50 patients with T3 supraglottic carcinomas.…”

Section: Therapy Of Primarily Diagnosed Laryngeal Cancermentioning

confidence: 99%

“…In former times, open partial laryngectomy represented a high percentage of interventions. Today the indication of open surgery of T1 and T2 tumors of the larynx is only rarely made in western industrial nations because retrospective case series showed similar oncologic results of open partial laryngectomy and transoral laser surgery for supraglottic and glottic carcinomas but an increased perioperative morbidity of open partial resection [57], [59], [79]. In particular classic vertical partial resections are more and more rarely applied.…”

Section: Therapy Of Primarily Diagnosed Laryngeal Cancermentioning

confidence: 99%

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Evidence and evidence gaps of laryngeal cancer surgery

Wiegand

2016

GMS Current Topics in Otorhinolaryngology - Head and Neck Surgery; 15:Doc03

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Section: Therapy Of Primarily Diagnosed Laryngeal Cancermentioning

confidence: 99%

Section: Therapy Of Primarily Diagnosed Laryngeal Cancermentioning

confidence: 99%

Evidence and evidence gaps of laryngeal cancer surgery

Wiegand

2016

GMS Current Topics in Otorhinolaryngology - Head and Neck Surgery; 15:Doc03

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“…Die postoperative Aspiration ist passager und meist nur gering ausgepr ä gt. Daher sind sekund ä re permanente Tracheotomien und Laryngektomien aus funktionellen Gr ü nden nur selten notwendig [30,150,155,158,199,215,216] . Faktoren, die wesentlich die Wiedererlangung der Schluckfunktion nach supraglottischer Larynxteilresektion, ob transzervikal oder endoskopisch durchgef ü hrt, beeinfl ussen sind: die oropharyngeale Transitzeit des Bolus, der Schluss der Atemwege am Kehlkopfeingang, die Position des Restlarynx in Relation zum Zungengrund, die Bewegung des Zungengrunds an die Rachenhinterwand und die Elevation des Restlarynx [214,217,218] .…”

Section: Funktionelle Ergebnisseunclassified

Funktionserhaltende Therapie des Kehlkopf- und des Hypopharynxkarzinoms

Ambrosch¹,

Fazel²

2011

Laryngo-Rhino-Otol

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The principles of open vs. laser microsurgical approaches for partial resections of the larynx are described, oncological as well as functional results discussed and corresponding outcomes following primary radiotherapy are opposed. Over the last decade, the endoscopic partial resection of the larynx has developed to an accepted approach in the treatment of early glottic and supraglottic carcinomas thus leading to a remarkable decline in the use of open surgery. Comparing the various surgical approaches of laryngeal partial resections, the oncological outcome of the patients, as far as survival and organ preservation are concerned, are comparable, whereas functional results of the endoscopic procedures are superior with less morbidity. The surgical procedures put together, are all superior to radiotherapy concerning organ preservation. Transoral laser microsurgery has been used successfully for vocal cord carcinomas with impaired mobility or fixation of the vocal cord, supraglottic carcinomas with infiltration of the pre- and/or paraglottic space as well as for selected hypopharyngeal carcinomas. It has been well documented that laser microsurgery achieves good oncological as well as functional results with reasonable morbidity. However, patients with those tumours have been successfully treated by open partial resections of the larynx at medical centres with appropriate expertise. The initially enthusiastic assessment of study results concerning the efficacy of various protocols of chemoradiation with the intent of organ preservation for laryngeal and hypopharyngeal carcinomas are judged more cautious, today, due to recent reports of rather high rates of late toxicity complications.

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“…& Organ-preserving laser surgery in early laryngeal cancer has shown equal survival rates as radical surgery but with improved functional outcome [3]. & Some departments offer complex reconstructions with pedicled and increasingly free flaps after extensive tumor removal to maintain better functional outcome.…”

Section: Introductionmentioning

confidence: 99%

Changing the Perspective: Current Trends in the Assessment of Functional Outcome in Patients with Head and Neck Cancer

Tschiesner

2011

Curr Oncol Rep

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Functional outcome and quality of life have become frequent outcome measures in head and neck cancer (HNC) clinical trials. Many thoroughly validated outcome measures are available. Still, there is a low degree of standardization and comparability among measures. It seems difficult to fully translate the new insights into clinical routine. The aims of this paper are 1) to acknowledge the diversity of outcome measures and many of the past milestones that have been reached, but also 2) to capture a growing need to concentrate and reach consensus. The hypothesis is to gain more benefit from changing the perspective toward consensus rather than diversity in functional outcome assessment. The next steps are to adopt a unique "language" to describe functional outcome and implement clear end points that assist clinical decision making. The International Classification of Functioning, Disability, and Health was adopted by the WHO and offers an internationally accepted classification to describe disability in HNC.

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Evaluation of available surgical management options for early supraglottic cancer

Abstract: Larynx-preserving surgical modalities offer comparable oncologic results with total laryngectomy in early supraglottic cancer. In addition, laser surgery has a lower incidence of complications and better functional results compared with open partial or total laryngectomy.

Cited by 35 publications

References 30 publications

Evidence and evidence gaps of laryngeal cancer surgery

Evidence and evidence gaps of laryngeal cancer surgery

Funktionserhaltende Therapie des Kehlkopf- und des Hypopharynxkarzinoms

Changing the Perspective: Current Trends in the Assessment of Functional Outcome in Patients with Head and Neck Cancer

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