“…First, for humane reasons the animal experiments were carried out while they were under general anesthesia, whereas in humans, the objective would be to perform the procedure with the patient under local anesthesia. However, our current method of choice for secondary TEP, which involves passing a mini‐tracheostomy tube through the trachea into the esophagus under TNE guidance, is similar in many ways . We perform this using topical anesthesia in the nose and throat to facilitate TNE, and local anesthetic injected into the posterior tracheal wall at the puncture site.…”