New device for single-stage in-office secondary tracheoesophageal puncture: Animal studies

Lau, David P.; Chng, Chin Boon; Chui, Chee-Kong

doi:10.1002/hed.23392

Cited by 12 publications

(6 citation statements)

References 15 publications

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“…In contrast, in a group of 58 patients with cT1/T2 parotid gland carcinoma analysed by Stenner et al, cervical occult metastases (without intra/periparotid) were found in only 5.1% of patients [3]. Among all presented series, only in the material by Lau et al, there was no statistical significance detected for variables associated with local stage [14]. Patients’ age turned out to be a significant clinical risk factor in three series and male sex in one series [2, 5, 13].…”

Section: Discussionmentioning

confidence: 99%

“…Based on the own material and literature (Table 3), it is obvious that the most important statistically significant risk factors for metastases to cervical lymph nodes are grade (7/10 series) and local stage: T (6/10) and its indicators, i.e. the size of the tumour (2/10), extraglandular infiltration (4/10) and nerve VII paresis (4/10) [2, 4, 5, 7, 10–14]. In the presented material, there was a high proportion of occult metastases observed (30%) and even though we did not observe statistical significance for T, in a uni- and multivariate analysis, we showed a significant effect of extraparotid extension, which in TNM classification appears in T3.…”

Section: Discussionmentioning

confidence: 99%

“…As pointed out in the literature, regional metastases are most common in SCC, AC NOS, MEC, CXPA, SDC, UCa and less common in AcCC and AdCC [2–4, 10, 11, 14, 15]. …”

Section: Discussionmentioning

confidence: 99%

“…Without doubt, the most prevalent location of occult metastases was level II (approximately 70%), which should not be surprising, since the tail of the parotid gland lies anatomically in the neck [14]. I, III and V levels were involved in approximately 20% (±3%), while level IV was involved in only one series (<10%).…”

Section: Discussionmentioning

confidence: 99%

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Probability and pattern of occult cervical lymph node metastases in primary parotid carcinoma

Stodulski

Mikaszewski

Majewska

et al. 2016

Eur Arch Otorhinolaryngol

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The present study was undertaken to evaluate real probability and pattern of cervical occult lymph node metastases (OLNM) in primary parotid carcinoma (PPC). We carried out a retrospective analysis of 66 patients treated in years 1992–2010 due to PPC, who underwent elective neck dissection (END). In search of risk factors for OLNM, we analysed the following parameters: age, sex, pT-Status, tumour size, skin invasion, facial nerve palsy, tumour fixation, extraparotid extension, localization, grade, histology, intra/periparotid LN metastases (IPLNM). OLNM was observed in 30.3% of patients. In a univariate analysis statistical significance was found for IPLNM, extraparotid extension and high risk histology. A multivariate analysis showed statistical significance only for the first variable. The most common location of cervical OLNM was level II (80%), then III (45%) and V (30%). In a compilation of our own material with data from the literature (5 series), we obtained a group of 80 patients with OLNM, selected out of 650 patients with cN0 (12.3%). The proportion of metastases to particular levels was the following: 69%—II, 22.5%—III, 20%—I,16%—V, 7.5%—IV. END should be carried out in case of all T3/T4a carcinomas with minimal range of levels II and III. Removal of levels Ib and Va is recommended as well. In the T1/T2 carcinomas with high grade/high risk histology, END should be performed including levels II and III.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…As pointed out in the literature, regional metastases are most common in SCC, AC NOS, MEC, CXPA, SDC, UCa and less common in AcCC and AdCC [2–4, 10, 11, 14, 15]. …”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Probability and pattern of occult cervical lymph node metastases in primary parotid carcinoma

Stodulski

Mikaszewski

Majewska

et al. 2016

Eur Arch Otorhinolaryngol

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“…Moreover, Lim et al [22] might have been the first to find that compared to patients without IPN metastasis, patients with a cN0 neck with IPN metastasis are more likely to develop locoregional recurrence. In a study published by Klussmann et al [23], univariate analysis revealed IPN involvement as an additional significant risk factor of tumour recurrence in 55 patients with pN+ tumours. Nisa et al [24] reported that decreased disease-free survival could be expected in patients with IPN involvement.…”

Section: Discussionmentioning

confidence: 99%

Predictors of distant metastasis in parotid acinic cell carcinoma

Fang

et al. 2019

BMC Cancer

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Background Distant metastasis (DM) is a common treatment failure pattern in acinic cell carcinoma (AciCC) of the major salivary glands; therefore, the main goal of this study was to analyse the predictors of DM in parotid AciCC. Methods Consecutive patients with surgically treated parotid AciCC who were followed for at least 5 years were retrospectively reviewed. Data regarding age, sex, TNM stage, pathologic characteristics, surgical treatment, and follow-up examinations were collected and analysed. The primary end-point was DM control (DMC); the DMC survival was calculated from the date of surgery to the date of event or the latest follow-up examination and analysed by the Kaplan-Meier method. Independent prognostic factors were evaluated by the Cox proportional hazards method. Results A total of 144 patients were included. Positive intraparotid nodes (IPNs) were noted in 34 (31.8%) patients. High-grade transformation was noted in 12 (8.3%) patients. A total of 83 (57.6%) patients underwent neck dissection, and neck node metastasis was proven in 37 (44.6%, 37/83) patients. The 10-year DMC rate was 86%. The Cox model analysis confirmed IPN metastasis (1.854 [1.061–4.144], p = 0.011) and high-grade transformation (4.219 [1.948–15.553], p < 0.001) as independent predictive factors of the DMC survival. Conclusion IPN metastasis and high-grade transformation are independent prognostic factors of the DMC survival.

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Surgery for Malignant Parotid Gland Tumours

Poorten

2019

Salivary Gland Cancer

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New device for single-stage in-office secondary tracheoesophageal puncture: Animal studies

Abstract: We believe the MAID can facilitate single-stage office-based secondary TEP in postlaryngectomy patients.

Cited by 12 publications

References 15 publications

Probability and pattern of occult cervical lymph node metastases in primary parotid carcinoma

Probability and pattern of occult cervical lymph node metastases in primary parotid carcinoma

Predictors of distant metastasis in parotid acinic cell carcinoma

Surgery for Malignant Parotid Gland Tumours

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