Translation of Wound Devices into Practice—A Myth? Translation is the Process of Taking an Invention Through to Clinical Practice—How Successful Are We?

Richardson, M. I.; Mani, Raj

doi:10.1007/978-3-031-26110-7_14

Chronic Wound Management 2023

DOI: 10.1007/978-3-031-26110-7_14

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Translation of Wound Devices into Practice—A Myth? Translation is the Process of Taking an Invention Through to Clinical Practice—How Successful Are We?

M. I. Richardson¹,

Raj Mani

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2023

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Oxygen Saturation or Tissue Oxygen Determinations on Skin Whose Viability is at Risk

Richardson,

Mani

2023

The International Journal of Lower Extremity Wounds

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The triad of ischaemia, neuropathy, and infection are among the principal causes of lower extremity wounds that are commonly prevalent in patients with diabetic foot (DF) a condition in which peripheral arterial disease commonly co-exists. The prevalence of this condition is increasing globally and with it, the mounting costs of its management. One aspect of management is saving limbs and or digits, a crucial part of this process is assessing tissue viability of skin which is a focus of this review: there are other aspects which are well described in the literature. Amputations are offered to limit the damage resulting from acute/chronic ischaemia. Holstein measured skin perfusion pressure using a radioisotope clearance technique to describe critically ischaemic skin; he found 30 mm Hg as the threshold above which healing may reliably be expected. Recent advances in vascular surgery and related technology have informed evidence-based advice to revascularize and save limbs; in practice, this may leave a wound in the distal skin unhealed; managing these raises questions of tissue viability. Much effort has been made to manage, prevent and to better understand these lower extremity wounds using measurements of tissue oxygen, oxygen saturation and skin imaging. The measurement techniques and their relevant merits are examined in this article. Advances in wound management systems and protocols can also facilitate the repair processes, and those which can have a particular impact on restoring or maintaining tissue perfusion are also discussed in the article.

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Oxygen Saturation or Tissue Oxygen Determinations on Skin Whose Viability is at Risk

Richardson,

Mani

2023

The International Journal of Lower Extremity Wounds

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Translation of Wound Devices into Practice—A Myth? Translation is the Process of Taking an Invention Through to Clinical Practice—How Successful Are We?

Cited by 1 publication

References 14 publications

Oxygen Saturation or Tissue Oxygen Determinations on Skin Whose Viability is at Risk

Oxygen Saturation or Tissue Oxygen Determinations on Skin Whose Viability is at Risk

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