[Translated article] International consensus document on obstructive sleep apnea

Mediano, Olga; Mangado, Nicolás González; Montserrat, Josep M.; Alonso-Álvarez, M. Luz; Almendros, Isaac; Alonso-Fernández, Alberto; Barbé, Ferrán; Borsini, Eduardo; Caballero‐Eraso, Candelaria; Cano‐Pumarega, Irene; Villafranca, Félix de Carlos; Carmona-Bernal, Carmen; Alduenda, José Luis Carrillo; Chiner, Eusebi; Guevara, José Aurelio Cordero; Manuel, Luis de; Durán-Cantolla, Joaquín; Farré, Ramón; Franceschini, Carlos; Gaig, Carles; Ramos, Pedro Garcia; García‐Río, Francisco; Garmendia, Onintza; García, Teresa Gómez; Pondal, Silvia González; Lecube, Albert; Madrid, Juan Antonio; Carrasco, José Luis Martínez; Masa, Juan F.; Margalef, María José Masdeu; Pérez, Miguel Ángel Muñoz; Lis, Enrique Mirabet; Monasterio, Carmen; Soriano, Nieves Navarro; Fuente, Erika Olea de la; Plaza, Guillermo; Puertas, Francisco J.; Rabec, Claudio; Resano, Pilar; Rigau, David; Roncero, Alejandra; Ruı́z, Concepción; Salord, Neus; Saltijeral, Adriana; Rubio, Gabriel Sampol; Quiroga, Macarena Ángel; Capdevila, Óscar Sans; Teixeira, Carlos; Madueño, Francisco; Togeiro, Sônia Maria; Acevedo, María Fernanda Troncoso; Ramírez, Leslie Katherine Vargas; Urionaguena, Nerea Zabala; Egea, Carlos

doi:10.1016/j.arbres.2021.03.027

Cited by 25 publications

(71 citation statements)

References 51 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In the current study, we found that nocturnal hypoxemia as detected by T90 as a marker of OSA severity ( 18 ) was associated with HbA1c levels among patients with DM. Specifically, an increase in T90 and ODI levels were associated with increasing HbA1c levels even after adjusting for multiple confounders including age, gender, BMI, HTN, CAD, CKD, stroke, heart failure, and AF.…”

Section: Discussionmentioning

confidence: 53%

Effect of nocturnal hypoxemia on glycemic control among diabetic Saudi patients presenting with obstructive sleep apnea

et al. 2023

View full text Add to dashboard Cite

BackgroundObstructive sleep apnea (OSA) is a prevalent disease that is associated with an increased incidence of type II diabetes mellitus (DM) if left untreated. We aimed to determine the association between glycosylated hemoglobin (HbA1c) levels and both nocturnal hypoxemia and apnea-hypopnea index (AHI) among a Saudi patients with OSA.MethodsA cross-sectional study that enrolled 103 adult patients diagnosed with DM and confirmed to have OSA by full night attended polysomnography between 2018 and 2021. Those who presented with acute illness, chronic obstructive pulmonary disease (COPD)/restrictive lung diseases causing sleep-related hypoxemia, or no available HbA1c level within 6 months before polysomnography were excluded from the study. Univariate and multivariate linear regression analyses between HbA1c levels and parameters of interest were tested.ResultsSixty-seven (65%) of the studied population had uncontrolled DM (HbA1c ≥7%). In univariate regression analysis, there was a significant positive association between HbA1c, and sleep time spent with an oxygen saturation below 90% (T90), female gender, and body mass index (BMI) (p<0.05) but not AHI, or associated comorbidities (p>0.05). In the multivariate analysis, HbA1c was positively associated with increasing T90 (p<0.05), and ODI (p<0.05), but not with AHI (p>0.05).ConclusionNocturnal hypoxemia could be an important factor affecting glycemic control in patients with OSA suffering from DM irrespective of the severity of both diseases.

show abstract

Section: Discussionmentioning

confidence: 53%

Effect of nocturnal hypoxemia on glycemic control among diabetic Saudi patients presenting with obstructive sleep apnea

et al. 2023

View full text Add to dashboard Cite

show abstract

“…Still, only the average thickness increased in a statistically significant way (see table in Supplementary Materials, and Figure 4), and finally, no changes were observed in morphometric ONH parameters. Macular volume (mm 3 ) F(1.50) = 0.834; p = 0.365 CPAP (22) 6.9 ± 0.5 6.8 ± 0.5 (0.016) Surgery (10) 6.6 ± 0.2 6.8 ± 0.3 CPAP + surgery (23) 6.9 ± 0.3 6.9 ± 0.3 Total 6.9 ± 0.4 6.9 ± 0.4 In summary, analyzing OCT changes after CPAP and/or surgery, we found a substantial improvement in foveal thickness and RNFL average thicknesses in both groups. Still, we could not see a significant difference between them.…”

Section: Resultsmentioning

confidence: 99%

“…The most accepted marker for this disease's severity is the sleep studies apnea/hypopnea index (AHI). However, AHI only shows the number of times a patient presents respiratory events, but does not measure its effect on the body, which can vary between patients with a similar AHI [1,8,10,11]. Respiratory indices such as AHI have recently been associated with the severity of nasal disorders, especially in chronic rhinitic inflammatory states or nasal vascular hyperactivity [12].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Assessment of the Effectiveness of Obstructive Sleep Apnea Treatment Using Optical Coherence Tomography to Evaluate Retinal Findings

Tejero-Garcés

Puyuelo

Casas

et al. 2022

JCM

Self Cite

View full text Add to dashboard Cite

Retinal findings may change in patients with obstructive sleep apnea syndrome (OSAS). The present study aims to evaluate several retinal findings, such as macula layer thickness, the peripapillary retinal nerve fiber layer, and the optic nerve head in patients with OSAS, using optical coherence tomography (OCT); it also aims to monitor the result of several types of treatment of OSAS with OCT. A prospective comparative study was designed. Patients were recruited at a Sleep Unit of a University Hospital and underwent comprehensive ophthalmological examinations. Following exclusion criteria, fifty-two patients with OSAS were finally included. Patients were examined by OCT twice: once before treatment, and again after six months of treatment. In mild–moderate patients, where retinal swelling had been demonstrated, retinal thicknesses decreased [fovea (p = 0.026), as did inner ring macula (p = 0.007), outer ring macula (p = 0.015), and macular volume (p = 0.015)]. In severe patients, where retinal atrophy had been observed, retinal thickness increased [fovea (p < 0.001)]. No statistically significant differences in efficacy between treatments were demonstrated. In conclusion, OCT can evaluate the retina in patients with OSAS and help to monitor results after treatment. In severe OSAS, retinal thickness increased six months after treatment.

show abstract

“…Some authors were able to prove a correlation between sleepiness and AHI [ 37 , 38 , 39 ]. However, further statements based on an international consensus [ 40 ] and the majority of published papers [ 17 , 41 , 42 , 43 , 44 ] suggest that excessive daytime sleepiness is not clearly or linearly associated with AHI. One of those studies investigated the relationship among DISE, AHI, and ESS [ 17 ].…”

Section: Discussionmentioning

confidence: 99%

Drug-Induced Sleep Endoscopy Findings and Hypoglossal Nerve Stimulation Therapy Outcomes

Pordzik

Seifen

Ludwig

et al. 2023

JPM

View full text Add to dashboard Cite

Hypoglossal-nerve stimulation (HGNS) is an established second-line therapy for patients with obstructive sleep apnea (OSA). Existing studies investigating the effect of preoperative drug-induced sleep endoscopic (DISE) findings on HGNS outcomes have mainly focused on the apnea/hypopnea index (AHI) among polysomnography (PSG) parameters, and have less frequently tested other PSG parameters such as the apnea index (AI), hypopnea index (HI), oxygen desaturation index (ODI), snoring index, and arousal index, or patient-reported excessive daytime sleepiness. The aim of this study was to investigate the correlation between DISE findings and the above-mentioned metrics after HGNS therapy. We only included patients with DISE findings providing detailed information about the degree of the anteroposterior velar (APV), oropharyngeal lateral wall (OPLW), or tongue-base (BT) obstruction based on the velum, oropharynx, base of tongue, and epiglottis (VOTE) classification. The data of 25 patients (9 female (36%)) were retrospectively evaluated. The mean age at the date of implantation was 54.52 ± 9.61 years, and the mean BMI was 29.99 ± 3.97 kg/m2. Spearman’s rho correlation coefficients were calculated. Significant correlations were found between the degree of APV obstruction and postoperative HI (r = −0.5, p < 0.05), and between the degree of OPLW obstruction and postoperative snoring index (r = 0.42, p < 0.05). BT obstruction was strongly correlated with postoperative metrics such as AHI (r = −0.57, p < 0.01), AI (r = −0.5, p < 0.05), ODI (r = −0.57, p < 0.01), ∆ AHI (r = 0.58, p < 0.01), ∆ AI (r = 0.54, p < 0.01) and ∆ ODI (r = 0.54, p < 0.01). No significant correlation was found between DISE findings and postoperative Epworth Sleepiness Scale values. These findings suggest that preoperative DISE findings, especially the degree of BT obstruction, are important for predicting an HGNS therapy outcome.

show abstract

[Translated article] International consensus document on obstructive sleep apnea

Cited by 25 publications

References 51 publications

Effect of nocturnal hypoxemia on glycemic control among diabetic Saudi patients presenting with obstructive sleep apnea

Effect of nocturnal hypoxemia on glycemic control among diabetic Saudi patients presenting with obstructive sleep apnea

Assessment of the Effectiveness of Obstructive Sleep Apnea Treatment Using Optical Coherence Tomography to Evaluate Retinal Findings

Drug-Induced Sleep Endoscopy Findings and Hypoglossal Nerve Stimulation Therapy Outcomes

Contact Info

Product

Resources

About