Transitional Cell Carcinomas in Four Fishing Cats (Prionailurus Viverrinus)

Abstract

Transitional cell carcinomas (TCC) of the urinary bladder were diagnosed in four related fishing cats (Prionailurus viverrinus). The major clinical sign in each case was persistent hematuria unresponsive to medical therapy. Cystotomy and biopsy provided an antemortem diagnosis in three of the fishing cats before euthanasia because of progression of clinical signs. The diagnosis was made in the fourth cat after euthanasia because of renal failure. Hematuria improved temporarily in one of the cats diagnosed antemortem and treated with piroxicam and carboplatin. Attempts to isolate a herpesvirus in two of the cats failed. Histopathologic appearance of the TCC was similar to that described for other species. TCC metastasis to the lungs was noted at necropsy in one cat; metastatic disease was not noted in the other fishing cats on gross or histopathologic examination. TCC of the urinary bladder appears to be more prevalent in fishing cats than in other species of domestic or nondomestic felids.

Transitional cell carcinoma of urinary bladder with metastasis in lumbar vertebrae and spinal cord compression in an ocelot(Leopardus pardalis)

“…Although infrequent, metastastatic infiltration of urinary bladder TCC to the lumbar vertebra results in spinal cord compression, leading to clinical signs such as hindlimb paralysis (De Moura et al 2007), as observed in the oncelot of the present report. Hematuria is the most common clinical sign of bladder neoplasia in dogs and cats with TCC (Sutherland-Smith et al 2004), however was not observed this or other urinary signal in the present study.…”

“…In wild felines rare cases were described; all cases in small wild felines. Four cases of urinary bladder neoplasia was described the fishing cats (Prionailurus viverrinus) (Sutherland-Smith et al 2004).…”

Use of a balloon-expandable metallic stent to relieve malignant urethral obstruction in a cat

“…3,12,13 The pulmonary nodule detected during the initial examination of the cat described in the present report was a small solitary lesion, and results of histologic examination indicated that it was unrelated to the urinary bladder tumor. 3,12,13 The pulmonary nodule detected during the initial examination of the cat described in the present report was a small solitary lesion, and results of histologic examination indicated that it was unrelated to the urinary bladder tumor.…”

Felidae

“…Captive fishing cats have a high incidence of transitional cell carcinomas (TCC) (Sutherland-Smith et al, 2004). Mean age in affected cats is 10.8 years and no sex predilection has been noted.…”