Transitional Cell Carcinoma of the Urinary Tract: Radiologic-Pathologic Correlation

The hallmark of TCC is multiplicity and recurrence. Nearly 2-4% of patients with bladder cancer develop upper tract TCC, but 40% of patients with upper tract TCC develop bladder cancer. Diagnosis of upper tract TCC is heavily dependent on imaging. Understanding the appearances of upper tract TCC on the different imaging techniques used is important in the accurate interpretation of imaging studies. Newer techniques such as CT urography are now increasingly used instead of conventional excretory urography in the surveillance of the upper tract in patients with bladder cancer.

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“…Infundibular tumors may cause focal calyceal dilatation. When large, TCCs are infiltrative and may not distort the renal contour [15].…”

Section: Sonographymentioning

confidence: 99%

Imaging and Staging of Transitional Cell Carcinoma: Part 2, Upper Urinary Tract

Vikram

Sandler²,

Ng³

2009

American Journal of Roentgenology

151

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Section: Imaging Appearances Excretory Urographymentioning

confidence: 99%

“…TCC can appear as fixed, smooth or irregular, single or multi ple filling defects within the renal collecting systems [7]. On excretory urography, a papil lary lesion may absorb contrast material into its interstitium resulting in a "stipple" sign [7]. Although this sign has been described with TCC, it is nonspecific and can occur be cause of fungal lesions and blood clots [7].…”

Section: Imaging Appearances Excretory Urographymentioning

confidence: 99%

“…On excretory urography, a papil lary lesion may absorb contrast material into its interstitium resulting in a "stipple" sign [7]. Although this sign has been described with TCC, it is nonspecific and can occur be cause of fungal lesions and blood clots [7]. Renal TCC occasionally produces an ob structed infundibulum that creates a phan tom calyx that may fill early, late, or not at all [7].…”

Section: Imaging Appearances Excretory Urographymentioning

confidence: 99%

“…Risk factors for carcinoma among patients with hematuria include smoking, age of greater than 40 years, and occupational ex posure [7] (Appendix 1). Once the decision H ematuria has many causes rang ing from urinary tract infections to carcinoma.…”

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confidence: 99%

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Imaging of Hematuria

O’Connor

Fitzgerald

Maher

2010

American Journal of Roentgenology

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Conventional radiography has no role in the detection of renal or urothelial carcinoma. Low-dose CT offers much greater sensitivities for the detection of urinary tract calculi than radiography at doses equivalent to conventional radiography. Ultrasound alone is insufficient for imaging of hematuria. Using ultrasound alone, it is often difficult to differentiate renal transitional cell carcinoma from other causes of filling defects of the renal collecting system such as blood clots, sloughed papillae, or fungus balls. The prominence of the role of excretory urography in the evaluation of patients with hematuria has diminished, and MDCT urography is now preferred to excretory urography in most cases.

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Doppler sonographic diagnosis of primary transitional cell carcinoma of the ureter

Killi¹,

Çal²,

Pourbagher³

et al. 2000

J. Clin. Ultrasound

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Primary carcinoma arising in the urothelium of the ureter is rare, accounting for only 1% of all cancers of the upper urinary tract. We describe a case in which primary transitional cell carcinoma of the right ureter was sonographically detected in a 45‐year‐old woman. The mass exhibited tumoral vascularity on power Doppler sonography and spectral analysis. © 2000 John Wiley & Sons, Inc. J Clin Ultrasound 28:361–364, 2000.

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Transitional Cell Carcinoma of the Urinary Tract: Radiologic-Pathologic Correlation

Cited by 14 publications

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Imaging and Staging of Transitional Cell Carcinoma: Part 2, Upper Urinary Tract

Imaging and Staging of Transitional Cell Carcinoma: Part 2, Upper Urinary Tract

Imaging of Hematuria

Doppler sonographic diagnosis of primary transitional cell carcinoma of the ureter

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