Transitional Cell Carcinoma of the Lacrimal Sac Presenting With Bloody Tears

Azari, Amir A.; Kanavi, Mozhgan R.; Saipe, Noah; Lee, Vivian; Lucarelli, Mark J.; Potter, Heather D.; Albert, Daniel M.

doi:10.1001/jamaophthalmol.2013.2907

Cited by 16 publications

(14 citation statements)

References 4 publications

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“…Hemolacria or bloody tears is a very rare entity, that has many causes, including tumors[ 1 ] conjunctivitis, trauma, retrograde epistaxis, inflammatory polyps, hemangiomas,[ 2 ] and chloromas[ 3 ] to mention a few; but Munchausen syndrome can be seen with ophthalmic manifestations[ 4 ] and should be considered in the differential diagnosis when ocular abnormalities cannot be explained after a thorough evaluation. [ 5 6 ]…”

Section: Discussionmentioning

confidence: 99%

Bloody tears: A rare presentation of munchausen syndrome case report and review

Karadsheh

2015

J Family Med Prim Care

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We report a 16-year-old Jordanian female who presented with bleeding from both eyes of sudden onset. Her physical examination was remarkable for blood pouring from both eyes, and normal otherwise examination including eye and nose examination. During hospital stay, it was noted that “bleeding” occurred only when alone in the room. She later was seen to prick her finger tips of the left hand with her right hand using a hair clip. She denied any psychological problems, and later did not show for follow-up. Munchausen syndrome as a cause of bleeding is discussed.

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Section: Discussionmentioning

confidence: 99%

Bloody tears: A rare presentation of munchausen syndrome case report and review

Karadsheh

2015

J Family Med Prim Care

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“…1,7 Neoplasia therefore produces a variety of epithelial malignancies, including squamous cell, transitional cell, mucoepidermoid, adenoid cystic, and adenocarcinoma. 1,2 The majority arise de novo, though transformation of benign papillomas is not uncommon. 6 Transitional cell carcinoma is the second most common epithelial malignancy after squamous cell, accounting for 13% to 15% of tumors.…”

Section: Commentmentioning

confidence: 99%

“…4,8 Mean age at presentation is 50, while that for benign papillomas is nearly a decade younger. 2,3,4 Lacrimal sac carcinoma typically manifests with a firm, subcutaneous mass arising above the medial canthal tendon. This corresponds with the anatomic location of the minimally distensible fundus of the lacrimal sac; by contrast dacryoceles and chronic dacryocystitis protrude below the canthal tendon.…”

Section: Commentmentioning

confidence: 99%

“…1 Approximately 400 cases have been reported, including 37 of transitional cell carcinomas. 2,3 Epiphora, recurrent dacryocystitis, and palpable medial canthal masses are the most common initial symptoms. 4,5,6 We present the management of an unusual case of transitional cell carcinoma, in which a fungating skin lesion in the medial canthal region was the main finding at presentation.…”

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confidence: 99%

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Transitional Cell-Type Papillary Carcinoma of the Lacrimal Sac Manifesting as a Medial Canthal Skin Lesion

Erickson¹,

Modi²,

Ko³

et al. 2014

Orbit

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A 61-year-old man presented with a 2.5 cm fungating skin lesion above the right medial canthus, accompanied by fluctuance and subtle inferotemporal globe displacement. The tumor had erupted 2 months previously and grown rapidly. Computed tomography (CT) revealed a 4.2 × 2.8 × 2.1 cm exophytic mass of the right orbit, superimposed on chronic dacryocystitis. Incisional biopsy disclosed faulty epithelial maturation sequence with possible basement membrane invasion. The patient underwent wide excision with medial maxillectomy, inferior turbinectomy, ethmoidectomy, and partial rhinectomy. The orbital floor was then reconstructed; a paramedian forehead flap and myocutaneous cheek advancement flap were used to fill cutaneous defects. All surgical margins were negative on both frozen and permanent sections. Definitive histopathology was consistent with transitional cell type papillary carcinoma of the lacrimal sac. Adjuvant radiotherapy was recommended, but the patient has declined further treatment. He remains recurrence-free at one year.

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“…TCC comprises 2-11% of paranasal sinus tumors 1,2 and there are 38 published reports of TCC arising in the lacrimal sac. 3 Primary TCC of the conjunctiva has not to the authors knowledge previously been reported in the English literature, with only 1 previous French language report. 4 TCC of the bladder and urological tract, although morphologically similar, is considered a separate entity.…”

mentioning

confidence: 96%

Primary Transitional Cell Carcinoma of the Conjunctiva

Khan

Cameron

Torgersen

et al. 2017

Ophthalmic Plastic &Amp; Reconstructive Surgery

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A 77-year-old male presented with a large papillomatous conjunctival lesion on his lower eyelid. Biopsy and extensive systemic investigation revealed this to be a primary conjunctival transitional cell carcinoma. Patient preference and coexisting medical problems dictated conservative management with surgical debulking, topical mitomicin, and radiotherapy. Local control has been maintained for 4 years to date.

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Transitional Cell Carcinoma of the Lacrimal Sac Presenting With Bloody Tears

Cited by 16 publications

References 4 publications

Bloody tears: A rare presentation of munchausen syndrome case report and review

Bloody tears: A rare presentation of munchausen syndrome case report and review

Transitional Cell-Type Papillary Carcinoma of the Lacrimal Sac Manifesting as a Medial Canthal Skin Lesion

Primary Transitional Cell Carcinoma of the Conjunctiva

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