Transition Metal CatalysedC‐SCross‐Coupling Reactions at Room Temperature.

Abstract

Transition metal catalysed formation of Csp2-S bond through cross-coupling reaction stands important and powerful tools in synthetic organic chemistry. The reaction constitutes an important strategy for the synthesis of thioethers that possess diverse biological activities in medicine and agriculture. Nonetheless, maintaining reaction temperature during Csp2-S crosscoupling reaction decides fate of desired product along with possibility of by-product and disulfides. The economy of process, safety and environmental issue demands thioether synthesis at mild condition and room temperature. Only very few reactions were successful under mild condition using Pd, Cu, Ni, NiÀ Ir and Ir catalyst. The current prospective summarizes the best protocols used for efficient Csp2-S cross-coupling reactions by transition metal catalyst under mild condition.

A CuMoO4 nanocatalyst for Csp2–O cross-couplings; easy access to nitrofen derivatives

“…Based on the reactivity of CuMoO 4 and BaMoO 4 in C–S and C–N cross-coupling reactions and earlier DFT studies, 13,14 a tentative plausible mechanism is suggested (Scheme 6). From the control experiment, it is evident that the monometallic salts of copper and molybdenum independently or in situ are not effective for this cross-coupling reaction.…”

“…In initial screening experiments, iodobenzene 1a and phenol 2a were used as classical substrates to establish suitable reaction conditions (Table 1). In the first phase of the study, the classical conditions were assessed using 3 mol% of CuMoO 4 catalyst 14 in 1 mL of water solvent and 2 equiv. KOH.…”

“…CuO nano has also been reported for C sp 2 –O cross-coupling reactions for the synthesis of diaryl ethers. 12 We recently reported a CuMoO 4 catalyst for N -arylations, S -arylations, and Se -arylations, 13,14 a BaMoO 4 catalyst for S -arylations, and CuSeO 3 for Se -arylations. 15…”

A Triazole‐Based Covalent Gel Loaded with Cu/Pd Bimetallic Nanoparticles for Efficient Catalytic Cross‐Coupling Reactions

“…Cross‐coupling reactions are one of the effective, versatile and direct methods for constructing C−C bonds [1,2] . They have greatly promoted the development of organic chemistry and have been one of the most popular areas of organic chemistry with an indispensable and significance role for the synthesis of complex molecules.…”

“…Cross-coupling reactions are one of the effective, versatile and direct methods for constructing CÀ C bonds. [1,2] They have greatly promoted the development of organic chemistry and have been one of the most popular areas of organic chemistry with an indispensable and significance role for the synthesis of complex molecules. Among them, Pd-catalyzed Sonogashira-Hagihara and Mizoroki-Heck coupling reactions of aryl or vinyl halides with terminal alkynes or reactive olefins under alkaline conditions are important and commonly used reactions, and the coupling products have been widely used in pharmaceuticals, dyestuff, advanced materials, supramolecular chemistry, etc.…”