Transient Complete Heart Block Complicating Renal Ethanol Embolization

Zack,; Ferral, Héctor

doi:10.1016/s0009-9260(02)90978-5

Cited by 6 publications

(3 citation statements)

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“…Although side effects have been reported, they mainly consist of inadvertent embolization of untargeted vessels or postoperative symptoms of nausea, vomiting, and flank pain which is also known as “postinfarction syndrome” [15]. The fact that major systemic complications are rare [16] might be due to the more localized field of operation in RAE, as compared to AVMs, which may have a larger volume and allow easier access of ethanol to the systemic circulation.…”

Section: Discussionmentioning

confidence: 99%

Pulmonary Arterial Hypertension Secondary to Ethanol Sclerotherapy for Renal Artery Embolization

Saba

Davis

Balavenkataraman

et al. 2014

Case Reports in Critical Care

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Pulmonary arterial hypertension (PAH) has been reported as a major complication to consider and promptly manage in the use of ethanol sclerotherapy. Most of the available data on the development of PAH is derived from the use of ethanol for embolization of arteriovenous malformation, but it has been rarely reported in its other fields of application. We describe a case of outpatient renal artery embolization using ethanol, in which respiratory failure develops secondary to PAH despite adhering to safe practice protocols. We highlight the importance of pulmonary arterial pressure monitoring and the treatment steps to follow in order to avoid irreversible fatal outcomes.

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Section: Discussionmentioning

confidence: 99%

Pulmonary Arterial Hypertension Secondary to Ethanol Sclerotherapy for Renal Artery Embolization

Saba

Davis

Balavenkataraman

et al. 2014

Case Reports in Critical Care

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“…Initial clinical reports suggested that an ethanol dose of 0.56 mL per kilogram of body weight was usually adequate to ensure complete renal ablation (10). However, in clinical reports over the last 2 decades, the dose of ethanol used has been approximately 0.2 mL/kg (6,7,(11)(12)(13) because of potential toxicity, including coagulopathy and acute alcohol intoxication (5,(14)(15)(16). Our clinical experience has shown that large RCCs are not adequately embolized by using TAE at this ethanol dose level.…”

mentioning

confidence: 92%

Comparative Study of Transcatheter Renal Arterial Embolization with and without Closed Renal Circuit: Pharmacokinetic and Histologic Assessment in Pigs

Onozawa¹,

Murata²,

Shimizu³

et al. 2009

Radiology

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“…Initial clinical reports suggested that an ethanol dose of 1 ml per 4 pounds (1.8 kg) body weight is usually adequate to ensure complete renal ablation [6]. However, in the light of clinical studies conducted over the last two decades, ethanol doses have been reduced to approximately 0.2 ml/kg body weight [7][8][9][10][11] because of potential toxicity, including coagulopathy and acute alcohol intoxication [12][13][14][15]. As our own clinical experience suggests that large RCCs are not adequately embolized by TAE with an ethanol dose of 0.2 ml/kg body weight, we have developed a new technique, referred to as "TAE during aspiration of blood with absolute ethanol via a balloon-occluded drainage vein" (TAE-ABOD), to permit the use of higher doses of ethanol.…”

Section: Introductionmentioning

confidence: 99%

Pilot study of transcatheter arterial ethanol embolization under closed renal circuit for large renal cell carcinomas

et al. 2008

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The safety of a new technique, designated "transcatheter arterial embolization (TAE) with aspiration via a balloon-occluded renal drainage vein" (TAE-ABOD), for the management of large renal cell carcinomas (RCCs). The subjects were 25 patients with RCC who underwent a total of 27 sessions of TAE-ABOD. This TAE-ABOD technique incorporates two procedures: balloon occlusion of renal drainage vein and infusion of absolute ethanol into the tumor-feeding arteries during aspiration of blood via a balloon catheter, thereby reducing leakage of absolute ethanol into the systemic circulation. Our primary endpoint was to establish a safe regimen for high-dose ethanol injection therapy, and our secondary endpoint was to assess global survival of the patients. The administered dose of ethanol ranged from 0.2 to 0.5 ml/kg [median: 0.34 (SD: 0.10) ml/kg], increased in a stepwise manner. The systemic ethanol concentration was measurable in 14 patients, and was less than 0.1 mg/ml in 12 and from 0.1 to less than 0.2 mg/ml in two. There were no major complications such as renal failure or renal abscess. TAE-ABOD can safely deliver a high dose of absolute ethanol for the treatment of large RCCs.

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Transient Complete Heart Block Complicating Renal Ethanol Embolization

Cited by 6 publications

References 0 publications

Pulmonary Arterial Hypertension Secondary to Ethanol Sclerotherapy for Renal Artery Embolization

Pulmonary Arterial Hypertension Secondary to Ethanol Sclerotherapy for Renal Artery Embolization

Comparative Study of Transcatheter Renal Arterial Embolization with and without Closed Renal Circuit: Pharmacokinetic and Histologic Assessment in Pigs

Pilot study of transcatheter arterial ethanol embolization under closed renal circuit for large renal cell carcinomas

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