Transient apical ballooning accompanying respiratory infection

Brunetti, Natale Daniele; Leva, Riccardo; Passero, Tommaso; Dioguardi, Ezio; Montrone, Deodata

doi:10.3109/17482941.2012.682070

Cited by 11 publications

(5 citation statements)

References 7 publications

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“…Of a total of 1725 articles found [1341 with the precise Medical Subject Headings term (TTC)], we selected 26 articles dealing with 27 case reports (Table 1), 12 –37 with an expected higher prevalence of women (n = 20, 74.1%). The mean age was 61.4 ± 13.7 years and bacterial infections were more frequent (n = 23, 85.2%).…”

Section: Resultsmentioning

confidence: 99%

Takotsubo Cardiomyopathy and Acute Infectious Diseases

et al. 2014

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Takotsubo cardiomyopathy (TTC), also defined as "stress cardiomyopathy," is characterized by a systolic dysfunction localized in the apical and medial left ventricles. Takotsubo cardiomyopathy is more prevalent in females and it is usually related to an event triggered by physical or emotional stress. We systematically explored PubMed and Embase medical information source to identify case reports showing association between infection and TTC. For each kind of infection, we collected a set of data, including pathogen, site of infection, clinical outcome, patient age and sex, and author and year of publication. We found 26 articles dealing with 27 case reports (74% women). The mean age was 61.4 ± 13.7 years and bacterial infections were more frequent (n = 23, 85.2%). In 14 cases, there was a culture-based definition of the bacterial strain: gram+ in 8 cases (57.1%) and gram- in 6 cases (42.9%). Clinical outcome was always favorable.

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Section: Resultsmentioning

confidence: 99%

Takotsubo Cardiomyopathy and Acute Infectious Diseases

et al. 2014

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“…Prior studied have linked several infections to TTC, including pulmonary infection and upper respiratory tract infection [9] , [10] . De Giorgi et al reviewed 27 reported case related to acute infection-induced TTC, found that it most frequently affects female and caused by bacterial infections.…”

Section: Discussionmentioning

confidence: 99%

A rare manifestation of Takotsubo Cardiomyopathy associated with non-tuberculous mycobacterium

Saboe

Sari

Febrianora

2020

Journal of Clinical Tuberculosis and Other Mycobacterial Diseas

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Background Takotsubo Cardiomyopathy or broken heart syndrome is a rare cause of non-ischemic cardiomyopathy that produce left ventricular dysfunction with characteristic left ventricular apical ballooning. It rarely caused by infection. We present an atypical manifestation of non-tuberculous mycobacterial (NTM) infection with myocardial involvement and its diagnostic challenge. Case illustration A 57-year-old female presented with prolonged fever, fatigue and weight loss for one and half months. General examination was unremarkable with elevated C-Reactive Protein and normal troponin. Electrocardiogram (ECG) showed diffuse T wave inversion with prolonged QTc. Echocardiography showed hypokinetic apical with normal ejection fraction. Angiography showed patent coronary arteries. Ventriculography showed apical ballooning. Workup with ethambutol scan revealed active mycobacterial infection in both lung and mesentery. Sputum polymerase chain reaction (PCR) was positive for non-tuberculous mycobacterium. Follow up ECG and echocardiography showed improvement in QTc interval and left ventricular wall motion abnormalities. Results Takotsubo Cardiomyopathy may manifest as asymptomatic ventricular dysfunction following non-tuberculous mycobacterial infection. A thorough investigation will help identify the systemic disease with cardiac involvement which potentially could be fatal. Conclusion Takotsubo cardiomyopathy may be triggered by infection. Identification of causal is crucial as a management strategy to restore cardiac function.

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“…In other cases, apical ballooning was caused by phenylephrine inhaled for relieving nasal congestion [9]. Stress cardiomyopathy, however, is not uncommon even in case of respiratory infection [10].…”

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confidence: 99%