Transient and persistent photosensitivity due to musk ambrette. Clinical and photobiological studies

Ramsay, Colin A.

doi:10.1111/j.1365-2133.1984.tb06604.x

Cited by 22 publications

(2 citation statements)

References 28 publications

(33 reference statements)

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“…It has been suggested that chronic contact dermatitis from Compositae allergens could stimulate the skin's immune system by promoting recognition of endogenous neoantigens induced within the skin by irradiation alone (17). The presence of sensitizations to other allergens, like lichens or fragrances, in patients with clinical features of photodermatitis, has also been previously reported (18, 19), and they could also play a role in the development of CAD. The presence of phototoxic polyacetylenes in Compositae plants has also been used to explain the unclear connection between abnormal reactions to UV light and Compositae allergy (20).…”

Section: Discussionmentioning

confidence: 56%

Allergic contact dermatitis to plants in a Spanish dermatology department: a 7‐year review

2006

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To investigate the incidence of allergic contact dermatitis (ACD) to plants in our area, we reviewed the records of the patients that were studied in the Allergic Contact Unity of our hospital in the last 7 years (2248 patients). We found 69 cases of positive patch tests to plant allergens, representing 3% of all the patients in that period. Diallyl disulfide was the most frequent allergen (47 cases), involving mainly middle-aged housewives with chronic hand eczema. Positive tests to sesquiterpene lactone mix (SL mix) were found in 11 patients, mostly middle-aged rural workmen with an airborne clinical pattern. Other allergens detected were lichens, primin, tulipalin A and wood. These results show a high incidence of ACD to diallyl disulfide that, in our opinion, should be tested in all housewives or cooks with chronic hand eczema. The predominance of the classical airborne pattern of allergy to SL in our study may be because the airborne way of allergen exposure in our area, with a high percentage of rural population, is the most frequent, and it makes it important to remember this possibility in the differential diagnosis of photosensitivity.

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Section: Discussionmentioning

confidence: 56%

Allergic contact dermatitis to plants in a Spanish dermatology department: a 7‐year review

2006

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“…Most patients with TCSA-induced photodermatitis improved within a few weeks of allergen avoidance, but some patients developed persistent photosensitivity, with recurrent flares of dermatitis in sunlight despite the absence of TCSA, which was removed from soaps by October 1960 (4). Subsequently, more cases of PACD caused by other photoallergens like olaquindox and musk ambrette were reported (5)(6)(7)(8)(9). Although persistent light reactivity was also reported with other agents including musk ambrette, hexachlorophene, olaquindox, and ketoprofen (10,11), this entity is now considered a part of CAD spectrum (12)(13)(14)(15)).…”

Section: Historymentioning

confidence: 94%