Transfer of immunoglobulins IgG, IgA and IgM to lacteal secretions in the parturient sow and their absorption by the neonatal piglet

Porter, P.

doi:10.1016/0005-2795(69)90271-2

Cited by 104 publications

(53 citation statements)

References 19 publications

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“…Regarding the plasma protein content, a similar increase in total protein, albumin, alpha-2-, and beta-globulin was found from day 1 to 4 of life for all piglets, independently of the BC administration, surpassing the essential threshold level of IgG of 10 mg/dl previously suggested (Machado-Neto et al 1987;Carbrera et al 2012). Due to the epitheliochorial placentation, piglets are born without systemic immunity in form of Ig and disease resistance mainly relies on an adequate colostrum and IgG uptake (Porter 1969;Coalson and Lecce 1973;Klobasa et al 1981;Sangild 2003). Colostrum and milk offer both, high amounts of maternal cells (B and T cells) and other substances e.g.…”

Section: Doi: 1017221/8404-cjasmentioning

confidence: 99%

Effects of bovine colostrum on performance, survival, and immunoglobulin status of suckling piglets during the first days of life

Viehmann¹,

Unterweger²,

Ganter³

et al. 2015

Czech J. Anim. Sci.

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Supplementation of bovine colostrum (BC) has shown to improve growth performance, intestinal development, and immune response in early-weaned pigs. Little is known about whether BC may have similar effects in neonatal piglets. In the present study, the effect of BC supplementation on mortality, growth performance, and blood parameters (plasma proteins and white blood count) of suckling piglets in the first 10 days of life was investigated under practical conditions with special emphasis on low birth weight piglets. In total, 258 newborn piglets from 30 multiparous sows in a commercial breeding unit were randomly assigned to two different treatment groups. Piglets received either 1 ml of BC orally on days 1-3 of life (group BC, n = 128) or 1 ml of saline (0.9%) (control (CON) group; n = 130). Body weight was measured on days 1, 4, and 10 of life. Blood was collected on days 1 and 4 from 60 piglets per group. No differences in mortality, body weight, and average daily weight gain were observed between treatment groups in days 1-10. However, compared to CON, particularly in low birth weight piglets the administration of BC supported (P < 0.01) their survival. Group BC exhibited lower plasma total protein (P = 0.03) and beta-globulin (P = 0.02) concentrations compared to group CON. In conclusion, BC improved low and normal birth weight piglets' survival during their first 10 days of life. Further research is needed to clarify whether the survival rate is related to earlier gut closure indicated by lower plasma protein levels, which might be beneficial due to a lower uptake of potential antigenic substances.

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Section: Doi: 1017221/8404-cjasmentioning

confidence: 99%

Effects of bovine colostrum on performance, survival, and immunoglobulin status of suckling piglets during the first days of life

Viehmann¹,

Unterweger²,

Ganter³

et al. 2015

Czech J. Anim. Sci.

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“…Antiserum to swine IgG was raised in rabbits and prepared by the method of Porter (1969). This antiserum was absorbed with pure swine IgA coupled to Sepharose 4B (Pharmacia, Uppsala) and was monospecific when tested by immunoelectrophoresis and double diffusion analysis against purified immunoglobulins, serum, colostrum and milk.…”

Section: (V) Immunoglobulinsmentioning

confidence: 99%

Control of Parturition in the Sow Using Progesterone and Prostaglandin

Gooneratne¹,

Hartmann²,

McCauley³

et al. 1979

Aust. Jnl. Of Bio. Sci.

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The effect of progesterone and prostaglandin administration on the timing of farrowing was studied in three groups of 25 sows each .. Progesterone treatment (100 mg/day) on days 112, 113 and 114 of gestation (group I) significantly prolonged the gestation length to 116 A±0·4 (mean±s.e.) days compared to the control sows (group III; 115·5 ±O· 2; P < 0 ·05). Administration of prostaglandin (200 I1g Cloprostanol intramuscularly) on day 115 of gestation following progesterone treatment (group II) resulted in a gestation length of 116 ·0 ±0·1 days, with the sows farrowing 25 ·4± 1 ·0 h after the prostaglandin injection. 80 % of the sows farrowed between 0800 and 1700 h of day 116 of gestation.Plasma progesterone levels were maintained by the exogenous progesterone during treatment. At farrowing, higher levels of progesterone were observed in groups I and II compared to controls. Prostaglandin treatment did not significantly alter withdrawal of progesterone· in progesterone treated sows, suggesting that the actions of exogenous prostaglandin is primarily on the myometrium and the cervix.Hormonal treatment in late pregnancy did not have any adverse effects on piglet viability and growth rate, or subsequent reproductive performances of sows. Lactation was initiated normally, and the concentrations of lactose, protein, fat, IgG, Na +, Ca2+ and K + in colostrum and milk were similar in all groups during the first 5 days of lactation.

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“…Consequently, piglets are largely devoid of immunoglobulins at birth (Kim, Bradley & Watson, 1966;Porter, 1969;Dujin, 1971;Bourne et al, 1974) and colostral antibodies are of major importance for their survival.…”

Section: Introductionmentioning

confidence: 99%

The effect of vaccination regimen on the transfer of foot and mouth disease antibodies from the sow to her piglets

Francis

Black

1984

J. Hyg.

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SUMMARYFour groups of pregnant sows were inoculated with type 01 foot and mouth disease (FMD) oil emulsion vaccine at various times before farrowing and samples of the sow's serum, colostrum and milk, and piglet's serum, collected during the first week after farrowing, were analysed for FMD virus neutralizing activity.No FMD neutralizing antibodies were detectable in the piglets serum at birth but they were present 1.5 h after suckling and peak titres were reached 1-3 days later. There was no significant difference between the antibody titres of colostrum samples collected from different teats at farrowing. However, similar samples collected 3 days later showed significant (P < 0 005) fore to hind variation. The principal FMD virus neutralizing antibody class present in the sow's serum at farrowing and in their 3-day-old piglets was governed by the inoculation schedule employed. When the last vaccinations were given -30 days before farrowing (dbf) the predominant FMD virus neutralizing class was IgG. However, when the sows were vaccinated only -12 dbf the predominant class was IgM. A significant correlation was observed between the sow's serum titres and colostrum titres at farrowing (r = 0 90), and also between sows colostrum titres at farrowing and their 3-day-old piglets serum titres (r = 0 99).

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Transfer of immunoglobulins IgG, IgA and IgM to lacteal secretions in the parturient sow and their absorption by the neonatal piglet

Cited by 104 publications

References 19 publications

Effects of bovine colostrum on performance, survival, and immunoglobulin status of suckling piglets during the first days of life

Effects of bovine colostrum on performance, survival, and immunoglobulin status of suckling piglets during the first days of life

Control of Parturition in the Sow Using Progesterone and Prostaglandin

The effect of vaccination regimen on the transfer of foot and mouth disease antibodies from the sow to her piglets

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