Transfer hydrogenation of ketones catalyzed by a trinuclear Ni(II) complex of a Schiff base functionalized N-heterocyclic carbene ligand

Abubakar, Samaila; Ibrahim, Halliru; Bala, Muhammad D.

doi:10.1016/j.ica.2018.09.057

Cited by 28 publications

(13 citation statements)

References 70 publications

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“…The ligand precursor 1 and the metal complexes 3-5 (Fig. 1) were initially developed and reported as precatalysts in the transfer hydrogenation of ketones [11,12]. While the metal complex 2 was synthesized according to (Scheme 1) and has not been reported in any previous work.…”

Section: Synthesismentioning

confidence: 99%

Antimicrobial Activities of Co (III), Mono and Tri-nuclear Ni Complexes Containing Schiff base Functionalized Imidazolium based Ligands

Abubakar

Muktari

Dogara

2021

AJOCS

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We reported the antimicrobial activities of cobalt and nickel complexes containing imino-NHC ligands. Complex 2 was synthesized by direct reaction of the insitu generated free carbene from 2-[2-(3-benzylimidazol-1-yl)ethyliminomethyl]phenol ligand with NiCl2 diglyme while complexes 3-5 were previously reported as catalysts in the transfer hydrogenation reaction of ketones. The compounds 1-5 were screened for antimicrobial sensitivity test against four gram-negative bacteria Escherichia Coli (E-coli), Shigella, Klebsiella Pneumoniae (K. Pneumoniae) and Salmonella Typhi (S.Typhi) and a gram positive bacteria Staphylocossus aureus (S.aureus). At a varying concentrations of 100, 200, 300, 400 and 500 µg/mL, significant activities were recorded using disc diffusion methods. The cobalt complex 3 was found to have higher activities compared with the corresponding nickel complexes and among the three nickel complexes, nickel complex with pyridine as wingtip was found to be more active than the one with a benzyl group. Similarly, the nickel centre with mononuclear was found to be more active than the tri-nuclear nickel complex. Except for the cobalt complex 3 no activity was recorded against S. typhi for all the nickel compounds.

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Section: Synthesismentioning

confidence: 99%

Antimicrobial Activities of Co (III), Mono and Tri-nuclear Ni Complexes Containing Schiff base Functionalized Imidazolium based Ligands

Abubakar

Muktari

Dogara

2021

AJOCS

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“…The ligand precursors 1a and 1b were first reported by Bala's group [14,15]. The cobalt complex 2 and the iron complex 3 were prepared (Scheme 1) by the direct reaction of in situ generated free carbenes with CoBr 2 and [FeI(Cp)(CO) 2 ] a procedure similar to the one reported by [16].…”

Section: Synthesismentioning

confidence: 99%

Synthesis, Characterization and Antimicrobial Activities of Co (III) and Fe (III) Complexes of Imino-N-heterocyclic Carbenes Ligands

Abubakar

Muktari

Atiko

2021

CSIJ

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The synthesis and antimicrobial application of Co (III) and Fe (III) complexes of imine functionalized N-heterocyclic carbene (Imino-NHC) ligands is reported. The ligand precursors 1-(2-[(hydroxyl-benzylidene)-amino]-ethyl)-3-R-3H-imidazol-1-ium bromide where R = pyridyl (1a) and benzyl (1b) have been reported in our previous work. The in-situ generated ligands of 1a and 1b have been successfully coordinated to CoBr2 and [FeI(Cp)(CO)2] leading to the isolation of air-stable N^C^N^O four coordinate Co(III) complex 2 and a six-coordinate Fe(III) complex 3. The synthesised complexes were both found to be NMR inactive hence were characterize using FTIR and LRMS. The complexes were screened for antimicrobial activities against four gram-negative bacteria Escherichia Coli (E-coli), Shigella, Klebsiella pneumoniae (K. Pneumoniae) and Salmonella typhi (S. typhi) and a gram positive bacteria Staphylocossus aureus (S. aureus). The antimicrobial test was conducted using disc diffusion methods and based on the concentrations of 100, 200, 300, 400 and 500 µg/ mL, significant activities were recorded for both cobalt and the iron complexes.

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“…We planned to use compound 2 as part of a broader effort to develop novel polyfunctional ligands bearing Schiff base/N-heterocyclic carbene (SB/NHC) hybrid ligands, together with their transition-metal complexes, for applications in homogeneous catalysis. 21,22 The three products of the chloromethylation reaction were isolated as analytically pure compounds which were analyzed spectroscopically. Stacked 1 H NMR spectra highlighting the formation of products 2-4 from 1 are presented in Figure 1, from which the region δ = 3.5 and 5 ppm provides a convenient handle for monitoring the products of the reaction.…”

Section: Letter Syn Lettmentioning

confidence: 99%

Structural Identification of Products from the Chloromethylation of Salicylaldehyde

Kadwa

Friedrich²,

Bala

2018

Synlett

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In the functionalization of salicylaldehyde to give 5-(chloromethyl)salicylaldehyde, two byproducts [5-(hydroxymethyl)salicylaldehyde and 5,5′-methylenebis(salicylaldehyde)] were also isolated. Detailed characterizations and structural analyses of all three products by single-crystal X-ray diffraction, multinuclear NMR spectroscopy, high-resolution mass spectrometry, and IR spectroscopic techniques are presented and discussed. A strategy is presented for the preferential isolation of the two byproducts through column chromatography.

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Transfer hydrogenation of ketones catalyzed by a trinuclear Ni(II) complex of a Schiff base functionalized N-heterocyclic carbene ligand

Cited by 28 publications

References 70 publications

Antimicrobial Activities of Co (III), Mono and Tri-nuclear Ni Complexes Containing Schiff base Functionalized Imidazolium based Ligands

Antimicrobial Activities of Co (III), Mono and Tri-nuclear Ni Complexes Containing Schiff base Functionalized Imidazolium based Ligands

Synthesis, Characterization and Antimicrobial Activities of Co (III) and Fe (III) Complexes of Imino-N-heterocyclic Carbenes Ligands

Structural Identification of Products from the Chloromethylation of Salicylaldehyde

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