Transcutaneous posterior tibial nerve stimulation for treatment of the overactive bladder syndrome in multiple sclerosis: Results of a multicenter prospective study

Sèze, M. de; Raibaut, P.; Gallien, P.; Even-Schneider, Alexia; Denys, Pierre; Bonniaud, V.; Gamé, X.; Amarenco, G.

doi:10.1002/nau.20958

Cited by 162 publications

(128 citation statements)

References 29 publications

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“…Therapeutic options for storage symptoms vary and they include, with or without associated clean intermittent self-catheterization, conservative treatments such as anticholinergic drugs -although the published data provide limited evidence for their efficacy in MS [4,5]. In patients with severe bladder overactivity unresponsive to anticholinergics there is evidence for the use of bladder injections of botulinum toxin A [6,7] and also emerging evidence on the use of cannabinoids [8] and tibial nerve stimulation [9]. Surgical procedures, which have been advocated with varying success [10], are a last resort being irreversible, with a risk of major operative morbidity and long-term consequences; they include augmentation cystoplasty [11], in which the bladder is transected and repaired with a patch of ileum isolated from the small intestine, and urinary diversion [12].…”

Section: Introductionmentioning

confidence: 99%

Usefulness of sacral nerve modulation in a series of multiple sclerosis patients with bladder dysfunction

Andretta

Simeone

Ostardo

et al. 2014

Journal of the Neurological Sciences

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Objective: Bladder dysfunctions are common in multiple sclerosis (MS) often causing the most distressing symptoms. The aim of this paper was to evaluate the effectiveness of sacral nerve modulation (SNM) in this disease. Methods: We conducted an observational retrospective survey in 17 patients treated with SNM in the north-east of Italy, all complaining of bladder symptoms (storage in 41%, voiding in 24%, mixed in 35%) unresponsive to conventional therapies, with a mean follow-up of 52 ± 26 months and mean Expanded Disability Status Scale score of 5.8 ± 1.8. Results: 75% of patients reported significant and lasting improvement in bladder symptoms and in quality of life. We observed a statistically significant improvement in frequency, urgency, number of pads, residual volumes, number of catheterizations and in the voided volumes. In 5 out of 6 cases with mixed symptoms the stimulation was discontinued (device totally explanted or turned off) after a mean time of 66 months (range 10-84 months) after the implant, for disease progression or loss of efficacy. Conclusion: SNM could be an option in very selected cases of storage and voiding symptoms refractory to conservative treatments caused by a stable or slowly progressive MS considering its minimal invasiveness and reversibility. The poor results observed suggest avoiding this therapy in mixed symptoms and in cases of advanced disability.

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Section: Introductionmentioning

confidence: 99%

Usefulness of sacral nerve modulation in a series of multiple sclerosis patients with bladder dysfunction

Andretta

Simeone

Ostardo

et al. 2014

Journal of the Neurological Sciences

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“…The PTNS cycle consisted of 12 outpatient treatment sessions, each lasting 30 minutes. The residual urine volume was assessed using ultrasonography 24 hr after the last TPTNS [1,9].…”

Section: Methodsmentioning

confidence: 99%

“…Procedure TPTNS was applied unilaterally with two adhesive electrodes placed above and behind the medial malleolus at the ankle on dominant side [9] [ Fig. 1].…”

Section: Assessmentmentioning

confidence: 99%

Effects of percutaneous posterior tibial nerve stimulation on voiding dysfunctions in cerebral palsy: A case report

Alishahi¹,

Farjad²,

Manshadi³

2017

PUCR

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A B S T R A C TThe present study, conducted on three children with cerebral palsy who had voiding dysfunction. After collecting demographic information, symptoms of voiding dysfunctions were recorded. Then; we did an ultrasonographic evaluation of the bladder to measure residual urine volume. Physiotherapy treatment through percutaneous electrical stimulation of the posterior tibial nerve was performed in 12 sessions. Bladder ultrasonography was repeated after treatment. Abnormal residual urine volume became normal in patients with urinary retention. Percutaneous posterior tibial nerve stimulation reduces symptoms of voiding dysfunctions in children with cerebral palsy.

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“…However, the mainstay of available data are from non-neurogenic overactive bladder patients [35,36], but some recent studies also provided data from neurological patients, that is, MS and Parkinson's disease [37][38][39][40][41][42][43][44]. However, randomized controlled trials (RCTs) are lacking for PTNS and TTNS in the neurological population, and there are currently no long-term data or systematic data on HRQoL available.…”

Section: External Neuromodulationmentioning

confidence: 99%

The management of urinary incontinence in the male neurological patient

Mehnert

Kessler

2014

Current Opinion in Urology

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PURPOSE OF REVIEW: Urinary incontinence in male neurological patients is a very frequent problem but treatment remains challenging. Thus, we summarize and highlight the latest developments in the management of urinary incontinence in this specific patient population. RECENT FINDINGS: Intermittent self-catheterization, antimuscarinics, intradetrusor injections with onabotulinumtoxinA, augmentation cystoplasty, urinary diversion, and artificial urinary sphincter are the cornerstones of the armamentarium for treating neurogenic urinary incontinence. However, with the exception of onabotulinumtoxinA intradetrusor injections, level of evidence is often low and male-specific outcomes are virtually not available. Alternative conservative and/or minimally invasive procedures such as neuromodulation techniques and suburethral suspension devices provide promising data with apparently good safety and tolerability but still insufficient evidence lacking randomized control trials. SUMMARY: Standard options for treatment of urinary incontinence in neurological patients remain largely unchanged. Alternative treatment options, especially of conservative or minimally invasive character, have the potential to further broaden the therapeutic spectrum. While a higher level of evidence is needed to assess the potential of such therapeutic approaches, randomized controlled trials in the male neurological population present a challenge. To truly advance treatment of urinary continence in male neurological patients, well-designed, multicenter studies are warranted. Purpose of review Urinary incontinence in male neurological patients is a very frequent problem but treatment remains challenging. Thus, we summarize and highlight the latest developments in the management of urinary incontinence in this specific patient population. Recent findingsIntermittent self-catheterization, antimuscarinics, intradetrusor injections with onabotulinumtoxinA, augmentation cystoplasty, urinary diversion, and artificial urinary sphincter are the cornerstones of the armamentarium for treating neurogenic urinary incontinence. However, with the exception of onabotulinumtoxinA intradetrusor injections, level of evidence is often low and male-specific outcomes are virtually not available. Alternative conservative and/or minimally invasive procedures such as neuromodulation techniques and suburethral suspension devices provide promising data with apparently good safety and tolerability but still insufficient evidence lacking randomized control trials. SummaryStandard options for treatment of urinary incontinence in neurological patients remain largely unchanged. Alternative treatment options, especially of conservative or minimally invasive character, have the potential to further broaden the therapeutic spectrum. While a higher level of evidence is needed to assess the potential of such therapeutic approaches, randomized controlled trials in the male neurological population present a challenge. To truly advance treatment of urinary continence in mal...

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Transcutaneous posterior tibial nerve stimulation for treatment of the overactive bladder syndrome in multiple sclerosis: Results of a multicenter prospective study

Cited by 162 publications

References 29 publications

Usefulness of sacral nerve modulation in a series of multiple sclerosis patients with bladder dysfunction

Usefulness of sacral nerve modulation in a series of multiple sclerosis patients with bladder dysfunction

Effects of percutaneous posterior tibial nerve stimulation on voiding dysfunctions in cerebral palsy: A case report

The management of urinary incontinence in the male neurological patient

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