Abstract:Depression symptoms in patients with Amyotrophic Lateral Sclerosis (ALS) has been investigated using instruments not specific and may interfere in results 1-3. Given the evolution and physical impairment caused by ALS, the ALS Depression Inventory (ADI) was created in 2005 to assess depression symptoms in these individuals. Results have shown a reduction in 12 items also providing accurate measures of depression symptoms in severely paralyzed patients 4,5. In light of the instrument's accuracy in detecting dep… Show more
“…Traditionally, depression in patients with ALS has been measured using instruments that were not specific to the disease ( 19 ) and included other variables related to motor abilities, which hamper accurate diagnosis ( 16 ). These instruments include the Hospital Anxiety and Depression Scale (HADS) ( 20 ), and the Neuropsychiatric Inventory (NPI) ( 21 ), which measure delusions, hallucinations, dysphoria, anxiety, agitation/aggression, euphoria, disinhibi-tion, irritability/lability, apathy, aberrant motor activity in patients with dementia, the Beck Depression Inventory (BDI) ( 22 ); the Hamilton Depression Rating Scale (HDRS) ( 23 ), and the Patient Health Questionnaire (PHQ-9) ( 24 ).…”
Section: Measuring Depression In Als the Adi-12 Scalementioning
confidence: 99%
“…The ADI-12 scale has been translated into Portuguese ( 19 ), although not validated, and adapted and validated in Italian ( 16 ). The Italian validation was carried out in 85 patients with ALS, and the internal structure of the scale was analyzed using a principal component analysis with oblique rotation.…”
Section: Measuring Depression In Als the Adi-12 Scalementioning
“…Traditionally, depression in patients with ALS has been measured using instruments that were not specific to the disease ( 19 ) and included other variables related to motor abilities, which hamper accurate diagnosis ( 16 ). These instruments include the Hospital Anxiety and Depression Scale (HADS) ( 20 ), and the Neuropsychiatric Inventory (NPI) ( 21 ), which measure delusions, hallucinations, dysphoria, anxiety, agitation/aggression, euphoria, disinhibi-tion, irritability/lability, apathy, aberrant motor activity in patients with dementia, the Beck Depression Inventory (BDI) ( 22 ); the Hamilton Depression Rating Scale (HDRS) ( 23 ), and the Patient Health Questionnaire (PHQ-9) ( 24 ).…”
Section: Measuring Depression In Als the Adi-12 Scalementioning
confidence: 99%
“…The ADI-12 scale has been translated into Portuguese ( 19 ), although not validated, and adapted and validated in Italian ( 16 ). The Italian validation was carried out in 85 patients with ALS, and the internal structure of the scale was analyzed using a principal component analysis with oblique rotation.…”
Section: Measuring Depression In Als the Adi-12 Scalementioning
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