2012
DOI: 10.1016/j.margen.2011.08.005
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Transcriptome remodeling associated with chronological aging in the dinoflagellate, Karenia brevis

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Cited by 34 publications
(28 citation statements)
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“…, ), consistent with a secondary metabolite, the PKSs are among a large set of transcripts downregulated during stationary phase, which is consistent with a role in primary, rather than secondary metabolism (Johnson et al. ). There were no differences observed in PKS transcript levels expressed in a toxic isolate of K. brevis as compared to a nontoxic isolate when analyzed by microarray or qPCR.…”
Section: Discussionsupporting
confidence: 63%
“…, ), consistent with a secondary metabolite, the PKSs are among a large set of transcripts downregulated during stationary phase, which is consistent with a role in primary, rather than secondary metabolism (Johnson et al. ). There were no differences observed in PKS transcript levels expressed in a toxic isolate of K. brevis as compared to a nontoxic isolate when analyzed by microarray or qPCR.…”
Section: Discussionsupporting
confidence: 63%
“…Percentages of gene responses ranged from 1.1% to 29% (Okamoto and Hastings, 2003;Moustafa et al, 2010;Morey et al, 2011;Johnson et al, 2012). The present study revealed that 8.6% of genes responded to CuSO 4 .…”
Section: Transcriptomic Responses In Dinoflagellatesmentioning
confidence: 46%
“…With modern technological advances, recent molecular methods (e.g., microarray and next generation sequencing) could allow analyses of the genomes and transcriptomes of dinoflagellates (Okamoto and Hastings, 2003;Moustafa et al, 2010;Toulza et al, 2010;Yang et al, 2011;Johnson et al, 2012;Shoguchi et al, 2013;Zhang et al, 2014a,c;Lin et al, 2015;Xiang et al, 2015). This has increased our understanding of the extraordinary genomic features of dinoflagellates, particularly the evolution of the eukaryotic genome.…”
Section: Introductionmentioning
confidence: 99%
“…Using massively parallel signature sequencing (MPSS), Moustafa et al [19] found 73% of the transcriptome of Alexandrium tamarense unchanged under a variety of conditions. A similar magnitude of transcriptome restructuring is found concurrent with the entry into stationary phase in K. brevis (29%) [20] and Alexandrium minutum (36%) [21]. However, microarray and MPSS cannot determine what mechanism(s) are responsible for the measured changes in transcript abundance.…”
Section: Introductionmentioning
confidence: 85%