Transcriptome analysis revealed key signaling networks regulating ovarian activities in the domestic yak

Xu, Shuonan; Peng, Wei; Jia, Gong-Xue; Ma, Shike; Yang, Qi-En; Zhang, Jun; Zhang, Ruina

doi:10.1016/j.theriogenology.2020.02.023

Cited by 14 publications

(11 citation statements)

References 34 publications

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“…Such cases of follicular cysts during early postpartum were not reported earlier in yaks; however, the existence of cystic corpus luteum with consistent higher levels of progesterone has been reported in one of the yaks reared under semi-intensive system during non-breeding season (Sarkar et al, 2006). In another study based on histological examination of yak ovarian tissue during cold and warm season, Xu et al (2020) found that although a higher number of antral follicles grow on yak ovaries during non-breeding cold season, these follicles are not healthy and some of them become polycystic due to abnormal granulosa cell function. In earlier studies, it has been postulated that postpartum anovulatory anoestrus in dairy cows is not due to a lack of follicular development but the failure of a dominant follicle to ovulate (Roche et al, 2000, Sakaguchi et al, 2004.…”

Section: Discussionmentioning

confidence: 76%

“…These postpartum ovarian events are regulated and dependent on nutritional and endocrine milieu of the animal (Sakaguchi et al, 2004). Recently, Xu et al (2020) through histological examination of yak ovarian tissue during cold and warm season revealed that although a higher number of antral follicles grow on yak ovaries during non-breeding cold season, but these follicles are not healthy and some of them become polycystic due to abnormal granulosa cell function. However, no study so far reported has the detailed events of postpartum ovarian follicular development for resumption of cyclic activities in relation to the status of body reserves and nutritional metabolites in yak.…”

Section: Introductionmentioning

confidence: 99%

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Body status and blood metabolites profiles during resumption of postpartum ovarian activity in yak (Poephagus grunniens)

Paul

Krishnan

Deori

et al. 2021

Reprod Domestic Animals

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We examined the changes in body weight (BW), back-fat thickness (BFT) and blood metabolites in relation to postpartum (PP) ovarian activity status in twenty female yaks raised under semi-intensive system. BFT and ovarian activities, like follicle development, ovulation (OV) and corpus luteum (CL) development, were monitored from 4 to 15 weeks (wk) PP using ultrasonography. Resumption of ovarian activity was confirmed with ovulation of dominant follicle (DF) and subsequent CL development, and >1 ng/ml progesterone concentration in blood plasma sample after 1week of ovulation. Yaks were further classified as cyclic (with CL), acyclic (without CL), and cystic (with >25 mm follicular cyst; FC). Within 20 weeks PP, 60% yaks resumed cyclic ovarian activity, while 25% failed to initiate cycling activity, and 15% developed follicular cysts. In all categories of yak, BW gradually decreased (p < .05) till nadir; however, nadir reached earlier (p < .05) in acyclic yaks. BFT differed (p < .05) among the yak groups, but it tended to be higher in cyclic yaks as compared to acyclic and cystic. No difference (p > .05) in non-esterified fatty acids (NEFA) values was found among the different categories of yaks, whereas, beta-hydroxy butyrate (BHB) levels were higher in cystic animals as compared to acyclic and cyclic. Blood glucose levels decreased in all yaks during initial 2 weeks after calving. Our findings suggest that yaks with low BW, BFT and glucose levels, and higher BHB values were at risk of delayed resumption of ovarian activity and concomitant development of follicular cysts.

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Section: Discussionmentioning

confidence: 76%

Section: Introductionmentioning

confidence: 99%

Body status and blood metabolites profiles during resumption of postpartum ovarian activity in yak (Poephagus grunniens)

Paul

Krishnan

Deori

et al. 2021

Reprod Domestic Animals

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“…Panda et al (2002) concluded that Opn4 is required for light-induced circadian phase shifting, and OPNs play a pivotal role in non-image-forming responses to light, including physiological adaptations to ambient light [43][44]. PIK3R1 plays an important role in regulating ovarian activities in yak seasonal reproduction [45]. EGFLAM is involved in cellular growth, differentiation and proliferation, including angiogenesis and membrane fusion [46].…”

Section: Discussionmentioning

confidence: 99%

CircRNA Expression in Chicken Granulosa Cells Illuminated with Red Light

Wang

Guo

Chen

et al. 2020

Preprint

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Background Our previous work revealed that red light (RL) can improve egg production by Jinghai Yellow hens. Circular RNAs (circRNAs) are a novel non-coding RNAs, but the molecular mechanism underpinning their functions during follicular development of hens under monochromatic light remains unknown. Results We compared expression profiles of granulosa cells (GCs) of small yellow follicles (SYFs) from hens under RL and white light (WL). A total of 2,468 circRNAs were identified, of which 22 were differentially expressed (DE) between RL and WL groups. Host genes of DE circRNAs were enriched in ovarian steroidogenesis, and MAPK signalling and PI3K-Akt signalling pathways. Furthermore, DE circRNA_0320 and circRNA_0185 interact with miR-143-3p targeting FSHR, which is essential for GC differentiation and follicle development. Conclusions These findings will facilitate further analysis of the molecular mechanism of circRNAs in GCs of SYFs, and expand our understanding of follicle development, which could lead to increased egg production.

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“…GhBZR1, as a member of the BR signal transduction cascad, can be regulated by Gh14-3-3, and bind to the promoter of GhXTH1 to regulate ber initiation and elongation development [64]. As a xyloglucan endotransglycosidase gene, the expression of TCH4 is induced by auxin, BR, and environmental stimulus and is mainly expressed in trichomes, lateral root primordia, and elongating hypocotyls [65]. In this study, we identi ed three homologous genes of TCH4, which were mainly present in cluster 7 expression pattern.…”

Section: Major Genes Related To Phytohormones Signal Transduction Invmentioning

confidence: 99%

Transcriptome analysis reveals gene expression associated with fuzz fiber initiation regulated by high-temperature in Gossypium barbadense

Cheng

Longyan

Wei

et al. 2020

Preprint

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Background: Gossypium barbadense L. is the most important renewable source of textile fiber. Cotton fiber cell initiation and elongation are often affected by various environmental stimulus, such as high temperature. However, little is known about the underlying mechanisms of temperature regulating the fuzz fiber initiation.Results: In the present study, phenotypic observation revealed that high temperature (HT) accelerated the fiber development, improved fiber quality and induced fuzz fiber initiation. It has been proved that the fuzz fiber initiation was inhibited by low temperature (LT), and 4 days post-anthesis (DPA) was the key stage for fuzz fiber initiation. Based on comparative transcriptome analysis, a total of 43,826 differentially expressed genes (DEGs) were identified, of which 9,667 were involved in both fiber development and temperature response with 901 transcription factor genes and 189 genes related to plant hormone signal transduction. Further analysis of gene expression patterns revealed that 240 genes were involved in fuzz fiber initiation. Functional annotation revealed that the candidate genes related to fuzz initiation were significantly involved in asparagine biosynthetic process, cell wall biosynthesis and stress response. Furthermore, the expression trends of sixteen selected genes from the RNA-seq data were almost consistent with the results of qRT-PCR results.Conclusions: Our study revealed several potential candidate genes and pathways that related to fuzz fiber initiation induced by high-temperature and provided a new view of temperature-induced tissue and organ development in Gossypium barbadense.

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Transcriptome analysis revealed key signaling networks regulating ovarian activities in the domestic yak

Cited by 14 publications

References 34 publications

Body status and blood metabolites profiles during resumption of postpartum ovarian activity in yak (Poephagus grunniens)

Body status and blood metabolites profiles during resumption of postpartum ovarian activity in yak (Poephagus grunniens)

CircRNA Expression in Chicken Granulosa Cells Illuminated with Red Light

Transcriptome analysis reveals gene expression associated with fuzz fiber initiation regulated by high-temperature in Gossypium barbadense

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