Transcatheter renal artery embolization improves lung function in patients with autosomal dominant polycystic kidney disease on hemodialysis

Yamakoshi, Shiho; Ubara, Yoshifumi; Suwabe, Tatsuya; Hiramatsu, Rikako; Yamanouchi, Masayuki; Hayami, Noriko; Sumida, Keiichi; Hasegawa, Eiko; Hoshino, Junichi; Sawa, Naoki; Takaichi, Kennmei; Kawabata, Masateru

doi:10.1007/s10157-012-0619-1

Cited by 9 publications

(2 citation statements)

References 8 publications

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“…Lung function tests were performed using a spirometer (CHESTAC-7800; Chest M.I., Inc.) based on the American Thoracic Society standardization of spirometry (28). At least three maneuvers were performed by each participant (29). The best effort was recorded.…”

Section: Methodsmentioning

confidence: 99%

Sleep-Disordered Breathing in Patients with Polycystic Liver and Kidney Disease Referred for Transcatheter Arterial Embolization

Sumida

Hoshino

Suwabe

et al. 2015

Clinical Journal of the American Society of Nephrology

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Background and objectives Sleep-disordered breathing (SDB) is prevalent among patients with CKD, but its prevalence among patients with symptomatic autosomal dominant polycystic kidney disease (ADPKD) and its association with total liver and kidney volume remain unclear.Design, setting, participants, & measurements This study examined the association between height-adjusted total liver and kidney volume (htTLKV) and SDB in a cross-sectional study of 304 adult patients with symptomatic ADPKD who were hospitalized at Toranomon Hospital for transcatheter arterial embolization and who underwent pulse oximetry between April 2008 and November 2013. SDB was defined as having a 3% oxygen desaturation index of $15 events per hour of sleep. Logistic regression was performed with sex-specific quartiles of htTLKV as the main predictor, using patient data and comorbidities as covariates.Results Overall (54.6% women, mean age 56.269.4 years, 83.5% on hemodialysis), 177 of 304 patients (58.2%) had SDB. SDB was strongly associated with htTLKV quartiles, demonstrating that odds ratios (ORs) and 95% confidence intervals (95% CIs) for SDB were 1.63 (0.76 to 3.48), 2.35 (1.09 to 5.06), and 4.61 (1.98 to 10.7) for htTLKV quartiles 2-4 (P for trend, P=0.003), respectively. Older age (OR, 1.81 per 10 years; 95% CI, 1.29 to 2.55), male sex (OR, 3.87; 95% CI, 1.96 to 7.66), receiving hemodialysis (OR, 3.46; 95% CI, 1.62 to 12.1), and higher body mass index ($25 kg/m 2 ) (OR, 3.03; 95% CI, 1.08 to 8.52) were also associated with SDB.Conclusions In this highly selected population of patients with symptomatic ADPKD referred for transcatheter arterial embolization, SDB was highly prevalent and independently associated with higher htTLKV.Clin J Am Soc Nephrol 10: 949-956, 2015.

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Section: Methodsmentioning

confidence: 99%

Sleep-Disordered Breathing in Patients with Polycystic Liver and Kidney Disease Referred for Transcatheter Arterial Embolization

Sumida

Hoshino

Suwabe

et al. 2015

Clinical Journal of the American Society of Nephrology

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“…Dialysis is recommended as the first-line renal replacement therapy in ESRD patients with ADPKD[ 4 ]. However, kidneys with cysts continue to enlarge during the dialysis period, leading to significant complications[ 5 , 6 ], including dyspnea, abdominal pain, lumbago and persistent hematuria. To treat these problems, nephrectomy and renal transplantation could be performed.…”

Section: Introductionmentioning

confidence: 99%

Safety and efficacy of transcatheter arterial embolization in autosomal dominant polycystic kidney patients with gross hematuria: Six case reports

Sui,

Duan,

et al. 2024

World J Clin Cases

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BACKGROUND To retrospectively report the safety and efficacy of renal transcatheter arterial embolization for treating autosomal dominant polycystic kidney disease (ADPKD) patients with gross hematuria. CASE SUMMARY The purpose of this study is to retrospectively report the safety and efficacy of renal transcatheter arterial embolization for treating ADPKD patients with gross hematuria. Materials and methods: During the period from January 2018 to December 2019, renal transcatheter arterial embolization was carried out on 6 patients with polycystic kidneys and gross hematuria. Renal arteriography was performed first, and then we determined the location of the hemorrhage and performed embolization under digital subtraction angiography monitoring. Improvements in routine blood test results, routine urine test results, urine color and postoperative reactions were observed and analyzed. Results: Renal transcatheter arterial embolization was successfully conducted in 6 patients. The indices of 5 patients and the color of gross hematuria improved after surgery compared with before surgery. No severe complication reactions occurred. CONCLUSION For autosomal dominant polycystic kidney syndrome patients with gross hematuria, transcatheter arterial embolization was safe and effective.

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Volume Reduction in Enlarged Kidneys in Autosomal Dominant Polycystic Kidney Disease (ADPKD) Prior to Renal Transplant with Transcatheter Arterial Embolization (TAE): A Systematic Review and Meta-Analysis

Voss

Athreya

2018

Cardiovasc Intervent Radiol

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Transcatheter renal artery embolization improves lung function in patients with autosomal dominant polycystic kidney disease on hemodialysis

Abstract: Since TAE not only led to a significant decrease of renal volume in ADPKD patients with nephromegaly, but also improved lung function (both %VC and %FEV(1.0)), pulmonary dysfunction should be recognized as one of the extrarenal complications of ADPKD.

Cited by 9 publications

References 8 publications

Sleep-Disordered Breathing in Patients with Polycystic Liver and Kidney Disease Referred for Transcatheter Arterial Embolization

Sleep-Disordered Breathing in Patients with Polycystic Liver and Kidney Disease Referred for Transcatheter Arterial Embolization

Safety and efficacy of transcatheter arterial embolization in autosomal dominant polycystic kidney patients with gross hematuria: Six case reports

Volume Reduction in Enlarged Kidneys in Autosomal Dominant Polycystic Kidney Disease (ADPKD) Prior to Renal Transplant with Transcatheter Arterial Embolization (TAE): A Systematic Review and Meta-Analysis

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