Volume Reduction in Enlarged Kidneys in Autosomal Dominant Polycystic Kidney Disease (ADPKD) Prior to Renal Transplant with Transcatheter Arterial Embolization (TAE): A Systematic Review and Meta-Analysis

Abstract

Current studies conclude that TAE is an effective and minimally invasive option for reduction in renal volume in order to optimize patient outcome for renal transplantation and for relief of compression symptoms. Further prospective studies involving increased sample size and multiple centers should be pursued to establish evidence-based guidelines.

Use of a micro-balloon catheter in transcatheter arterial embolization of the renal artery for recurrence of symptoms of autosomal dominant polycystic kidney disease

“…Ye at al. (13) described in a systematic review and meta-analysis of the literature on TAE for ADPKD that all studies demonstrated similar success rates in renal volume reduction.…”

“…As to the embolic agents used in TAE for ADPKD, various agents have been employed in previous studies (3,7,(11)(12)(13). These included coils (3,10), absolute ethanol (7,11), and polyvinyl alcohol particles (12).…”

Graft Intolerance Syndrome in Children Treated with Kidney Embolization: A Case Report

“…Other indications for kidney embolization in pediatric nephrology are arterial aneurysms and arteriovenous malformations, functional exclusion and polycystic kidney disease before transplantation, angiomyolipoma (mainly in the context of tuberous sclerosis), and autosomal dominant polycystic kidney disease (ADPKD) before kidney transplantation [9] [10].…”

Clinical findings, underlying pathogenetic processes and treatment of vascular dysfunction in autosomal dominant polycystic kidney disease

“…However, not all individuals are candidates for this procedure. Transcatheter arterial embolization (TAE) of the renal arteries may provide a noninvasive method of reducing renal volume in ADPKD [ 119 ].…”