Transcatheter Mitral Valve Replacement in Native Mitral Valve Disease With Severe Mitral Annular Calcification

Guerrero, Mayra; Dvir, Danny; Himbert, Dominique; Ureña, Marina; Eleid, Mackram F.; Wang, Dee Dee; Greenbaum, Adam; Mahadevan, Vaikom S.; Holzhey, David; O’Hair, Daniel; Dumonteil, Nicolas; Rodés‐Cabau, Josep; Piazza, Nicolò; Palma, José Honório; Delago, Augustin; Ferrari, Enrico; Witkowski, Adam; Wendler, Olaf; Kornowski, Ran; Martinez–Clark, Pedro; Ciaburri, Daniel; Shemin, Richard J.; Alnasser, Sami; McAllister, David; Borggrefe, Martin; Kerendi, Faraz; Pavlides, Gregory; Sobrinho, José Jazbik; Attizzani, Guilherme F.; George, Isaac; Nickenig, G; Fassa, Amir; Cribier, Alain; Bapat, Vinayak; Feldman, Ted; Rihal, Charanjit S.; Vahanian, Alec; Webb, John G.; O’Neill, William W.

doi:10.1016/j.jcin.2016.04.022

Cited by 270 publications

(207 citation statements)

References 18 publications

(8 reference statements)

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“…Dado que en estos casos no hay fusión comisural, la estenosis mitral degenerativa no se puede tratar mediante CMP 143 . Si la estenosis mitral degenerativa es grave, un estudio preliminar indica que es factible el TAVI en posición mitral para los pacientes ancianos sintomáticos considerados inoperables si la anatomía es adecuada 152 . Para los pacientes con estenosis mitral grave combinada con valvulopatía aórtica grave, es preferible la cirugía siempre que no esté contraindicada.…”

Section: ©Esc 2017unclassified

Guía ESC/EACTS 2017 sobre el tratamiento de las valvulopatías

Baumgartner¹,

Falk²,

Bax³

et al. 2018

Revista Española de Cardiología

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Section: ©Esc 2017unclassified

Guía ESC/EACTS 2017 sobre el tratamiento de las valvulopatías

Baumgartner¹,

Falk²,

Bax³

et al. 2018

Revista Española de Cardiología

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“…Guerrero, et al reported the first-in-human percutaneous implantation of a balloon-expandable transcatheter valve in a native mitral valve [80]. The use of newer aortic THV technologies such as Lotus (Boston Scientific Corporation) and direct flow valves (direct flow medical) in the mitral position for severe MAC (mitral annular calcification) [81] with improved outcomes were observed [82].…”

Section: Transcatheter Valve Implantationmentioning

confidence: 99%

Rheumatic Mineralization of Aortic Valve and Anterior Mitral Leaflet—A Case Report

Muthiah¹

2017

CRCM

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Aim: To present the heterotopic ossification of left-sided heart valves due to rheumatic inflammation and biomineralization. Introduction: Calcification in the region of mitral-aortic continuity is significant at its origin and etiopathogenesis. The etiology of valvular calcification may be divided into 3 groups, namely, inflammation, degeneration and metabolic disturbances. Calcification of cardiac valve leaflets is most often due to rheumatic etiology in tropical nations. Case Report: A 52-year-old male developed sudden onset of light-headedness and palpitations due to atrial fibrillation. Transthoracic 2D echocardiography revealed calcification of anterior mitral leaflet and aortic valve which resembles a bone-like structure and the patient was advised double valve replacement. Conclusion: It was known that the cellular mechanisms play an important role in its genesis and therapeutic strategies are targeted to reverse this process by understanding its biological mediators.

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“…The expansion of PMC indications in the near future should deal with the promising perspectives of new transcatheter mitral valve implantations (TMVI), especially in severe mitral annulus calcification [15]. The available data are still limited and TMVI is often used as a last option for very high-risk patients, bringing 30-day mortality in mitral annulus calcification up to 20%.…”

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confidence: 99%