Transcatheter aortic valve implantation for high risk patients With severe aortic stenosis using the Edwards Sapien balloon‐expandable bioprosthesis: A single centre study with immediate and medium‐term outcomes

Abstract

At medium term follow-up, both transcatheter approaches demonstrated good valve durability with no cardiac-related mortality post hospital discharge.

2-Year Follow-Up of Patients Undergoing Transcatheter Aortic Valve Implantation Using a Self-Expanding Valve Prosthesis

“…The procedural success rate of only 73% compared with reported rates of 90% to 97% in more recent studies (2,(5)(6)(7)9) is related to learning phase factors as well as a very conservative definition used in this study requiring MACCE-free in-hospital survival, without which the technical success rate was 83%. Similarly, the 30-day mortality rate of 15.2% in this study appears to be high in the light of more recent TAVI studies, which report 30-day mortality rates of 6% to 10% (5)(6)(7)9). In addition to the learning curve issues and various improvements described, that might be related to a tendency to treat patients with less comorbidity today than in the early phase of TAVI, as is reflected in this paper.…”

Apical-access-related complications associated with trans-catheter aortic valve implantation☆☆☆

“…Data from the literature demonstrate a rate of 3-7% [15,21], if reported, and we observed a rate of 1% (two patients). As a combined end point, intraprocedural bleeding, postprocedural re-exploration and aneurysm formation significantly impaired survival in the present patient cohort (Fig.…”

Transcatheter aortic implantation of the Edwards-SAPIEN bioprosthesis: Insights on early benefit of TAVI on mitral regurgitation

“…The present study is the first to demonstrate that the previously reported benefit in MR grades after implantation of the Edwards prosthesis [2,3] is secondary to a reduction in MR grades in 50% of patients with MR at baseline without deleterious effects in the other 50% or in those without MR. Those later results are in contrast with those recently reported with the CoreValve system [4].…”

“…The impact of Transcatheter aortic valve implantation (TAVI) on MR is controversial. Two recent publications have reported improvement in MR grades following transcatheter aortic valve replacement with the Edwards-SAPIEN valve system [2,3]. These findings were not replicated with the CoreValve system [4].…”

“…Two recent publications have reported improvement in MR grades following transcatheter aortic valve replacement with the Edwards-SAPIEN valve system [2,3]. However in these 2 studies the improvement was not investigated on an individual patient basis and the mechanism (s) of the benefit was unclear.…”