Transbronchial Needle Aspiration in the Diagnosis of Endobronchial Malignant Lesions

Çağlayan, Benan; Aktürk, Ülkü Aka; Fidan, Ali; Salepçi, Banu; Özdoğan, Selçuk; Saraç, Gülşen; Torun, Elif

doi:10.1378/chest.128.2.704

Cited by 30 publications

(29 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In our population, the sensitivity and the diagnostic yield of C-TBNA for lung cancer have been found to be between 58-70% and 60-100%, respectively [Table 5]. [222325–28] In our study the sensitivity of C-TBNA for lung cancer was 66.6% which matches with the literature. Our diagnostic yield is lower than that is reported in the literature, yet it is still within the range and could still represent our learning curve.…”

Section: Discussionsupporting

confidence: 86%

Transbronchial needle aspiration "by the books"

et al. 2011

View full text Add to dashboard Cite

BACKGROUND:Training for advanced bronchoscopic procedures is acquired during the interventional pulmonology (IP) Fellowship. Unfortunately a number of such programs are small, limiting dissemination of formal training.OBJECTIVE:We studied success of conventional transbronchial needle aspiration (C-TBNA) in the hands of physicians without formal IP training.METHODS:A technique of C-TBNA was learned solely from the literature, videos and practicing on inanimate models at “Hands-On” courses. Conventional TBNA with 21 and/or 19 gauge Smooth Shot Needles (Olympus®, Japan) was performed on consecutive patients with undiagnosed mediastinal lymphadenopathy.RESULTS:Thirty-four patients (male 23), mean age 54.9 ± 11.8 years underwent C-TBNA. Twenty-two patients had nodes larger than 20 mms. Suspected diagnoses were malignancy in 20 and nonmalignant conditions in 14. Final diagnoses were malignancy 17, sarcoidosis 4, reactive lymph nodes 12, and tuberculosis 1. Final diagnosis was established by C-TBNA in 14 (11 malignancy, 3 sarcoidosis; yield 41.1%), mediastinoscopy in 14, transthoracic needle aspiration in 3, peripheral lymph node biopsies in 2 and by endobronchial biopsy in 1. Nodal size had an impact on outcome (P = 0.000) while location did not (P = 0.33). C-TBNA was positive in 11/20 when malignancy was suspected (yield 55%), while 3/14 when benign diagnosis was suspected (yield 21.4%) (P = 0.05). Sensitivity, specificity, PPV, NPV, and diagnostic accuracy were 66.6%, 100%, 100%, 65%, and 79.4%, respectively. There were no complications or scope damage.CONCLUSION:Conventional-TBNA can be learned by the books and by practicing on inanimate models without formal training and results similar to those published in the literature could be achieved.

show abstract

Section: Discussionsupporting

confidence: 86%

Transbronchial needle aspiration "by the books"

et al. 2011

View full text Add to dashboard Cite

show abstract

“…15 Caglayan et al reported increase in yield from 79% to 91% after addition of TBNA to CDTs. 16 Only TBNA was positive in 6 cases out of 57 cases i.e. additional yield of TBNA was 10.52% in diagnosis of lung malignancies.…”

Section: Discussionmentioning

confidence: 89%

Diagnostic yield of TBNA and bronchial biopsy in lung cancer

Kumari¹,

Gupta²,

Abhesheik³

2017

Int J Res Med Sci

View full text Add to dashboard Cite

Background: Lung cancer has been the most common cancer worldwide since 1985, both in terms of incidence and mortality. In India, approximately 63,000 new lung cancer cases are reported each year. The study was undertaken to detect diagnostic yield of bronchial biopsy and transbronchial needle aspiration in suspected cases of bronchogenic carcinoma.Methods: This was a prospective study including 57 patients having clinical and radiological features of malignancy. Endobronchial forceps biopsy (FB) and transbronchial needle aspiration cytology (TBNA) has been employed during fiber-optic bronchoscopy. The statistical analysis was done using chi-square test.Results: Out of total 57 patients, 43 were found malignant on FB plus TBNA. The majority of patients (59.45%) were found to have squamous cell carcinoma on biopsy followed by Adenocarcinoma (16.21%), Small cell carcinoma (13.51%) and untypable cases (10.81%). On TBNA majority of patients (41.93%) could not be typed into any of the specific subtype. Out of rest typable carcinoma majority were squamous cell carcinoma (35.48%). Sensitivity of TBNA in diagnosing lung malignancy was 67.6%. The yield of TBNA, FB and TBNA plus FB was 54.38%, 64.91% and 75.43% respectively. Additional yield of TBNA over FB was 10.52%.Conclusions: TBNA is a beneficial, safe and minimally invasive bronchoscopic technique and may be considered routinely during Fiberoptic Bronchoscopy procedure to increase the yield with insignificant side effects in the diagnosis of bronchogenic carcinoma.

show abstract

“…In our study the sensitivity, specificity, positive predictive value, negative predictive value and accuracy of the combination of TBNA with PET/CT for the correct diagnosis of lymph node staging was 67%, 100%, 100%, 76% and 84%, respectively. The 84% accuracy ratio of is not so high compare to the result of studies without PET/CT, 78% is reported in study of Bilaceroglu et al, 82% is in Uskul et al 79% in Caglayan et al 75.8% in Kacar et al, which may be due to difficulties in obtaining adequate lymph node sample (19,(25)(26)(27).…”

mentioning

confidence: 84%

“…TBNA has been shown to be a valuable tool for diagnosing and staging bronchogenic carcinoma, and also diagnosing benign mediastinal or hilar lymph nodes, although the yield varies widely from 65% to 80% for bronchogenic carcinoma, 60% to %85 for benign mediastinal or hilar lymph nodes (19)(20)(21)(22)(23)(24)(25)(26). Adding TBNA to conventional diagnostic methods (forceps biopsy, bronchial washing, bronchial brushing) increases the diagnostic success in lung cancer (25)(26)(27). TBNA is usually combined with CT, and in recent years with PET and PET/CT, to increase sensitivity and specificity.…”

mentioning

confidence: 99%