“…The ultrasound conditions used in this study were chosen to mimic clinical reality as close as possible; that is, a commercial ultrasound scanner was used and operated in its standard contrast imaging mode using a commercially available transducer. The selected transmit frequency of 2.5 MHz is typically used for abdominal CEUS imaging (Mischi et al 2015;Dong et al 2016;Hyvelin et al 2017;de Figueiredo et al 2019;Zhang et al 2020). The acoustic performance of the agents was measured both in vitro and in vivo using a diagnostic ultrasound scanner employed with a convex transducer (EPIQ 7G and C9-2, respectively, Philips Ultrasound Inc., WA, USA).…”