Tränenfilmosmolarität gesunder Probanden: Vergleichbarkeit zweier Osmometer

König, Susanna; Priglinger, Siegfried; Schaumberger, Markus; Messmer, Elisabeth M.

doi:10.1055/a-1155-6468

Cited by 3 publications

(1 citation statement)

References 24 publications

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“…Tavakoli et al found that, in vivo, both instruments displayed poor repeatability (83). Some studies have found that after treatment, the osmotic pressure of tears in patients with dry eye is significantly reduced (74)(75)(76)(77)(78)(79)(80)(81)(82)(83)(84)(85)(86). However, other studies have found that the osmotic pressure of tears does not change significantly after treatment (84)(85)(86)(87)(88).…”

Section: I-pen Tear Osmolarity Testmentioning

confidence: 99%

Advances in Dry Eye Disease Examination Techniques

Wang

et al. 2022

Front. Med.

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Dry eye-related ocular surface examination is very important in the diagnosis and treatment of dry eye disease. With the recent advances in science and technology, dry eye examination techniques have progressed rapidly, which has greatly improved dry eye diagnoses and treatment. However, clinically, confusion remains about which examination to choose, how to ensure the repeatability of the examination, and how to accurately interpret the examination results. In this review, we systematically evaluate previous examinations of dry eye, analyze the latest views and research hotspots, and provide a reference for the diagnosis and management of dry eye.

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Section: I-pen Tear Osmolarity Testmentioning

confidence: 99%

Advances in Dry Eye Disease Examination Techniques

Wang

et al. 2022

Front. Med.

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Evaluation of tear osmolarity measured by I-Pen osmolarity system in patients with dry eye

Park

Choi

Han

et al. 2021

Sci Rep

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This retrospective comparative study was to evaluate tear osmolarity measured by I-Pen osmolarity system (I-MED Pharma Inc, Dollard-des-Ormeaux, Quebec, Canada) in healthy subjects without dry eye disease (DED) and patients with DED, and its association with other ocular surface parameters. This study comprised 65 eyes of 65 patients. The ocular surface parameters including tear osmolarity with I-Pen osmometer of the patients who visited the refractive surgery center of Samsung Medical Center between January 1, 2020 and May 31, 2020 were retrospectively collected. The subjects were divided as asymptomatic normal group and symptomatic dry eye group. The distribution of tear osmolarity and its association with other ocular surface parameters were evaluated. Total thirty-two patients (32 eyes) were included in the control group, and 33 patients (33 eyes) were included in the DED group. Tear osmolarity was significantly higher in the DED group. Tear osmolarity was negatively correlated with tear break-up time, and the Schirmer test, and was positively correlated with Ocular Surface Disease Index symptom score. The cut-off value of 318 mOsm/L showed a sensitivity of 90.9% and specificity of 90.6% for diagnosing DED. The I-Pen osmometer can be considered suitable for use in the clinical setting, with good performance in DED diagnosis.

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Environmental Effects on Dry Eyes in Primary Sjogren's Syndrome

Park¹,

Paik²,

Kim³

2023

J Korean Ophthalmol Soc

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Purpose: To investigate the effects of humidity, temperature, and fine particulate matter (PM2.5) on dry eye disease (DED) parameters in primary Sjogren's syndrome patients.Methods: We retrospectively analyzed the medical records of 18 primary Sjogren's syndrome patients who underwent DED treatment and had more than two follow-up visits. Symptom Assessment in Dry Eye (SANDE) scores, tear secretion, tear film breakup times, ocular surface staining scores, and tear osmolarity were assessed. Temperature, humidity, and PM2.5 concentrations during the week before the patient visits were calculated using public data and their relationships with DED parameters were analyzed.Results: All patients were females, with an average age of 57.6 ± 12.4 years. High temperature was significantly correlated with humidity and PM2.5 concentration (p = 0.004 and = 0.006, respectively). The high humidity, high temperature, and low PM2.5 groups had lower SANDE scores (p = 0.017, = 0.063, and = 0.049, respectively) and tear osmolarity (p < 0.001, = 0.009, and < 0.001, respectively). Multiple regression analysis showed that temperature and humidity had stronger correlations with tear osmolarity (p = 0.005 and = 0.012, respectively) compared to PM2.5 concentrations.Conclusions: Ocular discomfort and tear osmolarity were correlated with temperature, humidity, and PM2.5 concentrations. Among the DED parameters, tear osmolarity was the most sensitive indicator of exposure to environmental factors.

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Tränenfilmosmolarität gesunder Probanden: Vergleichbarkeit zweier Osmometer

Cited by 3 publications

References 24 publications

Advances in Dry Eye Disease Examination Techniques

Advances in Dry Eye Disease Examination Techniques

Evaluation of tear osmolarity measured by I-Pen osmolarity system in patients with dry eye

Environmental Effects on Dry Eyes in Primary Sjogren's Syndrome

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Tränenfilmosmolarität gesunder Probanden: Vergleichbarkeit zweier Osmometer

Cited by 3 publications

References 24 publications

Advances in Dry Eye Disease Examination Techniques

Advances in Dry Eye Disease Examination Techniques

Evaluation of tear osmolarity measured by I-Pen osmolarity system in patients with dry eye

Environmental Effects on Dry Eyes in Primary Sjogren&apos;s Syndrome

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Product

Resources

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Environmental Effects on Dry Eyes in Primary Sjogren's Syndrome