Tramadol wound infiltration is not different from intravenous tramadol in children: a randomized controlled trial

Giraldes, Ana Laura Albertoni; Sousa, Ângela Maria; Slullitel, Alexandre; Guimarães, Gabriel Magalhães Nunes; Santos, Melina Geneviève Mary Egan; Pinto, Renata Evangelista; Ashmawi, Hazem Adel; Sakata, Rioko Kimiko

doi:10.1016/j.jclinane.2015.08.009

Cited by 6 publications

(1 citation statement)

References 27 publications

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“…Implementation of bupivacaine infused collagen-matrix implant resulted in improved postoperative analgesia and lower opioid use for up to 72 h compared to placebo [150]. Single-shot WI before skin closure with tramadol (1 mg/kg) reduced pain scores and analgesic use compared to WI with bupivacaine, but this difference could be attributed to systemic resorption of tramadol [49,151]. WI with meloxicam (7.5 mg) offered no efficacy advantage over systemic administration, but could potentially elicit fewer systemic adverse events [50].…”

Section: Inguinal Herniorrhaphymentioning

confidence: 99%

Updates on Wound Infiltration Use for Postoperative Pain Management: A Narrative Review

Stamenković

Bezmarević

Bojić

et al. 2021

JCM

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Local anesthetic wound infiltration (WI) provides anesthesia for minor surgical procedures and improves postoperative analgesia as part of multimodal analgesia after general or regional anesthesia. Although pre-incisional block is preferable, in practice WI is usually done at the end of surgery. WI performed as a continuous modality reduces analgesics, prolongs the duration of analgesia, and enhances the patient’s mobilization in some cases. WI benefits are documented in open abdominal surgeries (Caesarean section, colorectal surgery, abdominal hysterectomy, herniorrhaphy), laparoscopic cholecystectomy, oncological breast surgeries, laminectomy, hallux valgus surgery, and radical prostatectomy. Surgical site infiltration requires knowledge of anatomy and the pain origin for a procedure, systematic extensive infiltration of local anesthetic in various tissue planes under direct visualization before wound closure or subcutaneously along the incision. Because the incidence of local anesthetic systemic toxicity is 11% after subcutaneous WI, appropriate local anesthetic dosing is crucial. The risk of wound infection is related to the infection incidence after each particular surgery. For WI to fully meet patient and physician expectations, mastery of the technique, patient education, appropriate local anesthetic dosing and management of the surgical wound with “aseptic, non-touch” technique are needed.

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