Tramadol or fentanyl analgesia for ambulatory knee arthroscopy

Cagney, B.; Williams, Owen; Jennings, L.; Buggy, Donal J.

doi:10.1097/00003643-199903000-00008

Cited by 17 publications

(2 citation statements)

References 5 publications

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Section: Introductionmentioning

confidence: 99%

“…While the long‐term benefits of arthroscopic partial meniscectomy have been established, the immediate post‐operative period up to about 4 weeks after the intervention is characterised by symptoms including pain, impaired joint function and joint effusion [1]. Post‐operative pain is usually greater in the first 24 h after surgery [1]. This pain could be due to several events including soft tissue injury during surgery and due to the liberation of free radicals, cytokines and other hyperalgesic substances that form an integral part of the inflammatory process.…”

Section: Introductionmentioning

confidence: 99%

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Effects of Viscoseal, a synovial fluid substitute, on recovery after arthroscopic partial meniscectomy and joint lavage

Mathies

2005

Knee Surg Sports Traumatol Arthrosc

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This was a pilot, single blind, randomised, controlled study in patients requiring partial meniscectomy. The aim was to assess whether replacing the synovial fluid lost during arthroscopy with a hyaluronic acid-containing synovial fluid substitute (Viscoseal) would reduce the severity and duration of post-operative symptoms during the 4 weeks post-surgery, in comparison to the standard arthroscopy procedure alone. Fifty patients were randomly assigned to either undergo arthroscopic partial meniscectomy alone (control group: n=25) or to receive 10 ml Viscoseal into the joint at the end of the procedure (Viscoseal group: n=25). Forty patients (20 per group) completed the study. Despite the small patient population in this pilot study, some interesting results were obtained. On Day 1 after surgery, the mean values for pain at rest (VAS) increased in both groups but this increase was lower in the Viscoseal group (8.9+/-23.1 mm) than in the standard therapy group (20.0+/-25.9 mm) (Mann-Whitney statistic MW-S: P=0.0525) and remained in favour of Viscoseal for the first 3 days after surgery. Joint swelling decreased to a greater extent in the Viscoseal group with an observed superiority at Day 7 (MW-S: P=0.1187) and a proven superiority at Days 12 (MW-S: P=0.015) and 28 (MW-S: P=0.0072). Diclofenac intake was lower in the Viscoseal group from Day 3 to Day 28 with a proven superiority (LB-CI > 0.5) in favour of Viscoseal on Days 3 (MW-S: P = 0.0093), 4 (MW-S: P= 0.0075), and 7 (MW-S: P = 0.0195) indicating that the product had an NSAID-sparing effect. Viscoseal was safe and well-tolerated and no adverse reactions occurred during the study. These findings indicate that Viscoseal may be useful as a synovial fluid substitute after arthroscopy.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%