Effects of a synovial fluid substitute on early recovery after arthroscopic subacromial decompression of the shoulder

Muccioli, Giulio Maria Marcheggiani; Wykes, P.; Hundle, Bhagwant; Grassi, Alberto; Roatti, G; Funk, Lennard

doi:10.1007/s12306-014-0341-0

Cited by 2 publications

(1 citation statement)

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“…The literature is more limited with regard to its use in shoulder arthroscopy. A previous smaller study into the effects of instilling hyaluronan following subacromial decompression27 showed improved pain and function and no adverse events. We designed this trial as a prospective randomized single-blinded intervention in a larger cohort, allowing a more robust statistical analysis of outcome measures.…”

Section: Discussionmentioning

confidence: 83%

Does Hyaluronan improve pain or function following Arthroscopic Subacromial decompression (ASD) surgery of Shoulder? Results of a level 1 RCT

Sarda

Butt

Elnikety

et al. 2019

IJOO

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Background: Sodium hyaluronate (hyaluronan) can be used as a synovial fluid substitute following arthroscopic surgery. In this study, we examined its effect on pain and function following arthroscopic subacromial arthroscopic decompression (ASAD). Methodology: A prospective, randomized, and single-blinded design was used (13/LO0427) to compare the effect of a single postprocedure subacromial instillation of 10 ml hyaluronan, against 10 ml saline control. All patients had interscalene block along with general anesthesia and followed standard postoperative rehabilitation protocol. A power calculation for a 6-point difference in Oxford Shoulder Score (OSS) indicated a minimum sample size of 44. Participants were assessed preoperatively, and at 12 weeks using the following outcome measures -Oxford Shoulder Score (OSS), visual analog score (VAS), European quality of life score (EUROQOL), and Disability of the arm, shoulder, and hand (DASH) scores. Results: 46 patients were included for analysis. Both groups showed a mean improvement in OSS of 9 points ( P = 0.0001), DASH (10 points, P < 0.05), and EUROQOL (0.13, P < 0.05). No significant difference was observed between groups in any of the recorded outcomes. Apart from one case of frozen shoulder in each group, no other complications were noted. Conclusion: While both groups showed improved pain and function scores after ASAD, no significant difference was seen between groups receiving placebo or hyaluronan. The intervention is safe but, in this study, has not been shown to improve postoperative pain or function over ASAD alone. Level of evidence: I.

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Section: Discussionmentioning

confidence: 83%