Spinal cord injury (SCI) has been associated with a dismal prognosis—recovery is not expected, and the most standard interventions have been temporizing measures that do little to mitigate the extent of damage. While advances in surgical and medical techniques have certainly improved this outlook, limitations in functional recovery continue to impede clinically significant improvements. These limitations are dependent on evolving immunological mechanisms that shape the cellular environment at the site of SCI. In this review, we examine these mechanisms, identify relevant cellular components, and discuss emerging treatments in stem cell grafts and adjuvant immunosuppressants that target these pathways. As the field advances, we expect that stem cell grafts and these adjuvant treatments will significantly shift therapeutic approaches to acute SCI with the potential for more promising outcomes.
Rugby union is the fastest growing sport in the USA, and its growth is only expected to continue to climb with the approaching 2023 Rugby World Cup. Rugby union carries risk for general and sport-specific injury. Tackles and high-impact collisions are a regular component of the game, and although often compared to American football, rugby union carries a unique pattern of injuries, with certain injuries occurring at a significantly higher rate. This review is aimed at familiarizing our orthopaedic workforce to the sport of rugby union and the evaluation, diagnosis, and treatment of the rugby union athlete. Injury prevention strategies guided by epidemiology, risk factors, and mechanisms of injury in rugby union athletes are critical.
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