Trajectories and predictors of state and trait anxiety in patients receiving chemotherapy for breast and colorectal cancer: Results from a longitudinal study

Schneider, Annegret; Kotronoulas, Grigorios; Papadopoulou, Constantina; McCann, Lisa; Miller, Morven; McBride, Jackie; Polly, Zoe; Bettles, Simon; Whitehouse, Alison S.; Kearney, Nora; Maguire, Roma

doi:10.1016/j.ejon.2016.07.001

Cited by 26 publications

(18 citation statements)

References 43 publications

(71 reference statements)

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“…All of the latter factors have been shown-individually and collectively-to contribute to the exacerbation and/or maintenance of depressive symptoms. As a group, cancer patients' stress declines and moods improve with the start of treatment [14,15,57,58], and this general observation would likely apply to the majority of the sample (64 %). However, its applicability to the patients described here, as discussed below, is limited.…”

Section: Discussionmentioning

confidence: 95%

Newly diagnosed patients with advanced non-small cell lung cancer: A clinical description of those with moderate to severe depressive symptoms

Andersen

Valentine

et al. 2020

Lung Cancer

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Objectives: The aims of this observational study were to 1) accrue newly diagnosed patients with advanced-stage non-small cell lung cancer (NSCLC) awaiting the start of first-line treatment and identify those with moderate to severe depressive symptoms and, 2) provide a clinical description of the multiple, co-occurring psychological and behavioral difficulties and physical symptoms that potentially exacerbate and maintain depressive symptoms. Materials and methods: Patients with stage IV NSCLC (N = 186) were enrolled in an observational study (ClinicalTrials.gov Identifier: NCT03199651) and completed the American Society of Clinical Oncology-recommended screening measure for depression (Patient Health Questionnaire-9 [PHQ-9]). Individuals with none/mild (n = 119; 64 %), moderate (n = 52; 28 %), and severe (n = 15; 8 %) depressive symptoms were identified. Patients also completed measures of hopelessness, generalized anxiety disorder (GAD) symptoms, stress, illness perceptions, functional status, and symptoms. Results: Patients with severe depressive symptoms reported concomitant feelings of hopelessness (elevating risk for suicidal behavior), anxiety symptoms suggestive of GAD, and traumatic, cancer-specific stress. They perceived lung cancer as consequential for their lives and *

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Section: Discussionmentioning

confidence: 95%

Newly diagnosed patients with advanced non-small cell lung cancer: A clinical description of those with moderate to severe depressive symptoms

Andersen

Valentine

et al. 2020

Lung Cancer

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“…We found that caregivers of patients who were admitted due to treatment‐related complications had lower QOL. This may because these events are not predictable and compound anxieties related to undergoing treatment . Notably, reason for hospitalization was only weakly associated with caregiver QOL, and the association disappeared when varying cut points for continuous variables.…”

Section: Discussionmentioning

confidence: 96%

“…This may because these events are not predictable and compound anxieties related to undergoing treatment. 52 Notably, reason for hospitalization was only weakly associated Abbreviation: MOS, Medical Outcomes Study. a Data are given as percentage, unless otherwise indicated.…”

Section: Discussionmentioning

confidence: 99%

Understanding Caregiver Quality of Life in Caregivers of Hospitalized Older Adults With Cancer

Hsu

Nathwani

Loscalzo

et al. 2019

J American Geriatrics Society

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BACKGROUND/OBJECTIVES Caregivers of older adults with cancer assist both with cancer care and other health issues, which may make them vulnerable to consequences of caregiving. Hospitalization may represent a time when a caregiver's ability to provide care at home is exceeded. We sought to characterize caregivers of hospitalized older adults with cancer, determine their quality of life (QOL), and identify factors associated with caregiver QOL. METHODS Patients (n = 100), aged 65 years and older, with an unplanned hospitalization and their caregivers were included. Caregivers completed a questionnaire about their health, social support, caregiving relationship, QOL (Caregiver Quality of Life Index‐Cancer [CQOLC] tool), and patient function. Patient medical history was obtained via chart review. The association between patient, caregiving, and caregiver factors and CQOLC was determined using multivariate linear regression. RESULTS Most patients (73%) had metastatic/advanced disease, and 71% received treatment for their cancer within 30 days of hospitalization. Median Karnofsky Performance Status (KPS) was 60%, and 89% required help with instrumental activities of daily living, as reported by caregivers. Median caregiver age was 65 years (range = 29‐84 years). The majority (60%) had no major comorbidities and rated their health as excellent/good (79%), though 22% reported worsening health due to caregiving. Caregivers had a median Mental Health Inventory‐18 score of 70 (range = 0–97), a median Medical Outcomes Study (MOS)‐social activity score of 56 (range = 0–87.5), and a median MOS‐Social Support Survey score of 68 (range = 0–100). Caregivers provided a median of 35 hours of care per week (range = 0‐168 hours of care per week). Mean CQOLC was 84.6 ± 23.5. Lower caregiver QOL was associated with poorer caregiver mental health, less social support, and poorer patient KPS (P < .05). CONCLUSION Caregivers of hospitalized older adults with cancer are older but generally in good health. Those with poorer mental health, less social support, and caring for patients with poorer performance status are more likely to experience lower QOL. J Am Geriatr Soc 67:978–986, 2019.

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“…Thus, improving the early diagnosis of anxiety may lead to better survival and quality of life. The time point before the start of chemotherapy was identified as one of the most anxiety-provoking time periods and may call for interventions (31). Our method for assessing time perception by prospective estimation of a one-minute interval is relatively simple and fast to perform.…”

Section: Discussionmentioning

confidence: 99%

Fast time perception is associated with high levels of anxiety in cancer patients prior to starting chemotherapy

Donev¹,

Ivanova

Conev

2020

BST

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Trajectories and predictors of state and trait anxiety in patients receiving chemotherapy for breast and colorectal cancer: Results from a longitudinal study

Cited by 26 publications

References 43 publications

Newly diagnosed patients with advanced non-small cell lung cancer: A clinical description of those with moderate to severe depressive symptoms

Newly diagnosed patients with advanced non-small cell lung cancer: A clinical description of those with moderate to severe depressive symptoms

Understanding Caregiver Quality of Life in Caregivers of Hospitalized Older Adults With Cancer

Fast time perception is associated with high levels of anxiety in cancer patients prior to starting chemotherapy

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