Traitement pharmacologique des troubles du comportement post-traumatiques

Rodet-Belarbi, Isabelle; Perrouin-Verbe, B.; Rome, Jeffrey D.; Bernat, Claire; Mathé, J

doi:10.1016/s0168-6054(02)00353-7

Cited by 12 publications

(1 citation statement)

References 53 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…La prescription de psychotropes reste fréquente, et les recommandations sont difficiles à asseoir sur des preuves de bon niveau, compte tenu de la faible qualité méthodologi-que des études conduites [3][4][5]. Par ailleurs, les effets secondaires de ces traitements sont fréquents et potentiellement graves.…”

Section: Introductionunclassified

Traitement pharmacologique des troubles du comportement post-traumatiques: prescrire ou ne pas prescrire ?

Beaufils

Ferrapie

Saoût

et al. 2009

Lett Med Phys Readapt

View full text Add to dashboard Cite

Section: Introductionunclassified

Traitement pharmacologique des troubles du comportement post-traumatiques: prescrire ou ne pas prescrire ?

Beaufils

Ferrapie

Saoût

et al. 2009

Lett Med Phys Readapt

View full text Add to dashboard Cite

Effectiveness of Pharmacotherapy for Depression after Adult Traumatic Brain Injury: an Umbrella Review

et al. 2022

View full text Add to dashboard Cite

Symptoms of depression are common following traumatic brain injury (TBI), impacting survivors’ ability to return to work, participate in leisure activities, and placing strain on relationships. Depression symptoms post TBI are often managed with pharmacotherapy, however, there is little research evidence to guide clinical practice. There have been a number of recent systematic reviews examining pharmacotherapy for post TBI depression. The aim of this umbrella review was to synthesize systematic reviews and meta-analyses of the effectiveness of pharmacotherapy for the management of post TBI depression in adults. Eligible reviews examined any pharmacotherapy against any comparators, for the treatment of depression in adults who had sustained TBI. Seven databases were searched, with additional searching of online journals, Research Gate, Google Scholar and the TRIP Medical Database to identify published and unpublished systematic reviews and meta-analyses in English up to May 2020. A systematic review of primary studies available between March 2018 and May 2020 was also conducted. Evidence quality was assessed using Joanna Briggs Institute Critical Appraisal Instruments. The results are presented as a narrative synthesis. Twenty-two systematic reviews were identified, of which ten reviews contained a meta-analysis. No new primary studies were identified in the systematic review. There was insufficient high quality and methodologically rigorous evidence to recommend prescribing any specific drug or drug class for post TBI depression. The findings do show, however, that depression post TBI is responsive to pharmacotherapy in at least some individuals. Recommendations for primary studies, systematic reviews and advice for prescribers is provided. Review Registration PROSPERO (CRD42020184915).

show abstract

Psychiatric disturbances after traumatic brain injury: Neurobehavioral and personality changes

Warriner

Velikonja²

2006

Curr Psychiatry Rep

View full text Add to dashboard Cite

Traumatic brain injuries (TBI) are frequently accompanied by psychiatric disturbances, which can include striking to relatively minor alterations in personality, behavior, and emotional regulation. The persistence of these neurobehavioral syndromes often leads to deleterious effects on recovery and rehabilitation outcomes. A recent surge of studies has emerged in the past several years to quantify the extent of psychiatric disorders in TBI and to describe differential clinical presentations. Various pre- and post-injury factors also have been hypothesized to contribute to the development and maintenance of psychiatric symptoms in survivors of brain injuries. The identification of high-risk individuals with distinct neuropathophysiological and psychosocial features permits the development of multidisciplinary and tailored approaches to the assessment, prevention, and management of the negative effects of personality and behavioral changes in TBI. This article summarizes the most recent research in these areas and highlights the gaps that need to be filled in subsequent future.

show abstract

Traitement pharmacologique des troubles du comportement post-traumatiques

Cited by 12 publications

References 53 publications

Traitement pharmacologique des troubles du comportement post-traumatiques: prescrire ou ne pas prescrire ?

Traitement pharmacologique des troubles du comportement post-traumatiques: prescrire ou ne pas prescrire ?

Effectiveness of Pharmacotherapy for Depression after Adult Traumatic Brain Injury: an Umbrella Review

Psychiatric disturbances after traumatic brain injury: Neurobehavioral and personality changes

Contact Info

Product

Resources

About